{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:59:21Z","timestamp":1788872361611,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,12,25]],"date-time":"2013-12-25T00:00:00Z","timestamp":1387929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Discovery Based Development","award":["P-10-11290"],"award-info":[{"award-number":["P-10-11290"]}]},{"name":"Ministry of Science and Technology"},{"DOI":"10.13039\/501100004192","name":"National Science and Technology Development Agency","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004192","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Thailand Research","award":["BRG5680001"],"award-info":[{"award-number":["BRG5680001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"Abstract<\/jats:title>\n \n Aim<\/jats:title>\n \n To measure the levels of\n hCAP<\/jats:styled-content>\n 18\/LL\u201037 in gingival crevicular fluid from patients with periodontal diseases compared with healthy controls and to determine the correlation between\n hCAP<\/jats:styled-content>\n 18\/LL\u201037 and chondroitin sulphate (CS) levels in patients with periodontitis.\n <\/jats:p>\n <\/jats:sec>\n \n Material and Methods<\/jats:title>\n \n Gingival crevicular fluid samples from 51 patients and 25 healthy volunteers were analysed for the\n hCAP<\/jats:styled-content>\n 18\/LL\u201037 levels by immunoblotting and were determined for the CS levels by the competitive enzyme\u2010linked immunosorbent assay.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Tris buffer\n pH<\/jats:styled-content>\n 9.85 was selected to recover\n hCAP<\/jats:styled-content>\n 18\/LL\u201037 from Periopaper strips, in which the percentages of recovery were around 70%. The median levels of\n hCAP<\/jats:styled-content>\n 18\/LL\u201037 in the aggressive and the chronic periodontitis (CP) groups were significantly greater than those in the gingivitis and the healthy groups (\n p\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.05). Significant correlations between the unprocessed 18\u2010\n kD<\/jats:styled-content>\n a fragment and CS levels (\n r\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.650;\n p\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.001) and between the mature 4.6\u2010\n kD<\/jats:styled-content>\n a fragment and CS levels (\n r\u00a0<\/jats:italic>\n =\n \u00a0<\/jats:italic>\n 0.502;\n p\u00a0<\/jats:italic>\n <\n \u00a0<\/jats:italic>\n 0.001) were observed only in the CP group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The significant correlations between the\n hCAP<\/jats:styled-content>\n 18\/LL\u201037 and the CS levels were found in CP, but not in aggressive periodontitis. The presence\n versus<\/jats:italic>\n absence of such correlations may be clinically applicable to help clinicians distinguish between two distinct types of periodontitis.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jcpe.12216","type":"journal-article","created":{"date-parts":[[2013,12,6]],"date-time":"2013-12-06T11:22:42Z","timestamp":1386328962000},"page":"252-261","source":"Crossref","is-referenced-by-count":12,"title":["Positive correlations between h\n CAP<\/scp>\n 18\/\n LL<\/scp>\n \u201037 and chondroitin sulphate levels in chronic periodontitis"],"prefix":"10.1111","volume":"41","author":[{"given":"Anupong","family":"Makeudom","sequence":"first","affiliation":[{"name":"Division of Clinical Immunology Department of Medical Technology Faculty of Associated Medical Sciences Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samakorn","family":"Kulpawaropas","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Periodontology Faculty of Dentistry, Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pattanin","family":"Montreekachon","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Periodontology Faculty of Dentistry, Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakornrat","family":"Khongkhunthian","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry and Periodontology Faculty of Dentistry, Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanapat","family":"Sastraruji","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Diagnostic Sciences Faculty of Dentistry Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peraphan","family":"Pothacharoen","sequence":"additional","affiliation":[{"name":"Thailand Excellence Center for Tissue Engineering and Stem Cells Department of Biochemistry and Center of Excellence for Innovation in Chemistry Faculty of Medicine Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prachya","family":"Kongtawelert","sequence":"additional","affiliation":[{"name":"Thailand Excellence Center for Tissue Engineering and Stem Cells Department of Biochemistry and Center of Excellence for Innovation in Chemistry Faculty of Medicine Chiang Mai University Chiang Mai Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suttichai","family":"Krisanaprakornkit","sequence":"additional","affiliation":[{"name":"Department of Oral Biology and Diagnostic Sciences Faculty of Dentistry Chiang Mai University Chiang Mai 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