{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T23:42:22Z","timestamp":1776469342948,"version":"3.51.2"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,5,14]],"date-time":"2014-05-14T00:00:00Z","timestamp":1400025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000389","name":"British Renal Society","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000389","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100016132","name":"JABBS Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100016132","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Chronic kidney disease (<jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content>) is associated with significant morbidity and mortality. There is a need to identify novel and modifiable risk factors in such patients. The periodontal component of the Renal Impairment In Secondary Care (<jats:styled-content style=\"fixed-case\">RIISC<\/jats:styled-content>) study aims to evaluate the association between chronic periodontitis and <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content> progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">RIISC<\/jats:styled-content> study is a prospective, observational cohort study of patients with <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content> from a renal clinic at a hospital in the West Midlands region of the <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>. Patients undergo a periodontal examination and plaque and saliva sampling. To benchmark the oral health status of the <jats:styled-content style=\"fixed-case\">RIISC<\/jats:styled-content> cohort, we compared it to the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>dult <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ealth <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>urvey 2009 (<jats:styled-content style=\"fixed-case\">ADHS<\/jats:styled-content>), a representative survey of the oral health of community dwelling adults in the <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the first 500 patients recruited into the <jats:styled-content style=\"fixed-case\">RIISC<\/jats:styled-content> study, 469 patients underwent a dental examination and 80 (17%) were edentulous. Among dentate subjects, patients within <jats:styled-content style=\"fixed-case\">RIISC<\/jats:styled-content> were significantly more likely to have any (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 4.0 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.7\u20135.9) or severe (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.8 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2.5\u20135.6) periodontitis compared to the <jats:styled-content style=\"fixed-case\">ADHS<\/jats:styled-content> sample.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence and severity of chronic periodontitis in this cohort of <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content> patients is markedly higher than a geographically matched control population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12263","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T15:12:44Z","timestamp":1397661164000},"page":"653-661","source":"Crossref","is-referenced-by-count":30,"title":["The periodontal health component of the Renal Impairment In Secondary Care (RIISC) cohort study: a description of the rationale, methodology and initial baseline results"],"prefix":"10.1111","volume":"41","author":[{"given":"Praveen","family":"Sharma","sequence":"first","affiliation":[{"name":"Periodontal Research Group School of Dentistry University of Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Dietrich","sequence":"additional","affiliation":[{"name":"Periodontal Research Group School of Dentistry University of Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amneet","family":"Sidhu","sequence":"additional","affiliation":[{"name":"Periodontal Research Group School of Dentistry University of Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viren","family":"Vithlani","sequence":"additional","affiliation":[{"name":"Periodontal Research Group School of Dentistry University of Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mutahir","family":"Rahman","sequence":"additional","affiliation":[{"name":"Periodontal Research Group School of Dentistry University of Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Stringer","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Jesky","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Okdeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Ferro","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Cockwell","sequence":"additional","affiliation":[{"name":"Department of Nephrology University Hospital Birmingham Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iain L. 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