{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:10:32Z","timestamp":1770819032526,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,6,1]],"date-time":"2014-06-01T00:00:00Z","timestamp":1401580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institutes of Health Clinical and Translational Award","award":["UL1 RR024148"],"award-info":[{"award-number":["UL1 RR024148"]}]},{"DOI":"10.13039\/100000097","name":"National Center For Research Resources","doi-asserted-by":"crossref","award":["KL2 RR024149"],"award-info":[{"award-number":["KL2 RR024149"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>In the Mexican\u2013American population, the prevalence of Type 2 diabetes mellitus (T2<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>) is as high as 50% of the population. This randomized controlled clinical trial was designed to elucidate how treatment of periodontal disease affects HbA1c values in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>One hundred and fifty\u2010four T2<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content> patients with periodontal disease were enrolled in the study. The test group was treated with scaling and root planing (<jats:styled-content style=\"fixed-case\">SRP<\/jats:styled-content>); the control group received oral hygiene instructions. At baseline and 4\u20136\u00a0weeks after therapy, a complete periodontal examination was performed. Blood was collected at baseline and 4\u00a0months later for HbA1c levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and twenty\u2010six individuals completed the study. Baseline mean\u00a0\u00b1\u00a0<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> HbA1c for the test and control groups were 9.0\u00a0\u00b1\u00a02.3% and 8.4\u00a0\u00b1\u00a02.0% respectively. Non\u2010significant difference in HbA1c reductions (0.6\u00a0\u00b1\u00a02.1% and 0.3\u00a0\u00b1\u00a01.7%) was found between test and control groups at 4\u00a0months. Comparisons of the periodontal clinical parameters between the test and control groups found significant differences with improved results in the test subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>No statistically significant differences were found in the changes of HbA1c levels between test and control groups. Non\u2010surgical periodontal therapy improved the magnitude of change in periodontal parameters as compared to the control subjects.<\/jats:p><jats:p>ClinicalTrials.gov Identifier: NCT01128374<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12268","type":"journal-article","created":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T23:57:49Z","timestamp":1399334269000},"page":"673-680","source":"Crossref","is-referenced-by-count":30,"title":["The effect of periodontal therapy on glycaemic control in a <scp>H<\/scp>ispanic population with type 2 diabetes: a randomized controlled trial"],"prefix":"10.1111","volume":"41","author":[{"given":"Isabel C.","family":"Gay","sequence":"first","affiliation":[{"name":"Dental School The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duong T.","family":"Tran","sequence":"additional","affiliation":[{"name":"Dental School The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana C.","family":"Cavender","sequence":"additional","affiliation":[{"name":"Dental School The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Weltman","sequence":"additional","affiliation":[{"name":"Dental School The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Chang","sequence":"additional","affiliation":[{"name":"Dental School The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estelle","family":"Luckenbach","sequence":"additional","affiliation":[{"name":"San Jose Clinic Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gena D.","family":"Tribble","sequence":"additional","affiliation":[{"name":"Dental School The University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2007.00983.x"},{"key":"e_1_2_6_4_1","volume-title":"National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States","author":"Centers for Disease Control and Prevention","year":"2011"},{"key":"e_1_2_6_5_1","volume-title":"Diabetes data & trends. 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