{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T05:44:19Z","timestamp":1782279859197,"version":"3.54.5"},"reference-count":46,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,7,12]],"date-time":"2014-07-12T00:00:00Z","timestamp":1405123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Research Support Foundation of the State of Maranh\u00e3o"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the association between periodontal status and serum biomarkers levels in haemodialysis patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study included 96 haemodialysis patients. The periodontal evaluation was realized using clinical attachment level (<jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content>), probing depth (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>), gingival bleeding index (<jats:styled-content style=\"fixed-case\">GBI<\/jats:styled-content>), visible plaque index (<jats:styled-content style=\"fixed-case\">VPI<\/jats:styled-content>) and gingival index (<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>). Biochemical and haematological data \u2013 serum albumin, phosphorus, creatinine, transferrin, ferritin, iron, alkaline phosphatase, calcium, potassium and haemoglobin \u2013 were collected from the medical records. The subject was diagnosed with periodontitis if he\/she had at least two inter\u2010proximal sites in different teeth with <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> \u22654\u00a0mm and\/or at least two inter\u2010proximal sites in separate teeth with <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> \u22655\u00a0mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study population consisted of 45\u00a0men and 51 women, with mean time under haemodialysis of 45.6\u00a0\u00b1\u00a033.1\u00a0months. Periodontitis was observed in 59.4% of the subjects. The periodontitis group had albumin (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.021) and phosphorus (<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.024) serum levels lower than the no periodontitis group. Thus, there was a positive association of periodontitis with hypoalbuminaemia (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a09.10, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.006) and a negative association with hyperphosphataemia (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a00.21, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.010).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings suggest that periodontitis is associated with albumin and phosphorus serum levels in haemodialysis patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12283","type":"journal-article","created":{"date-parts":[[2014,6,13]],"date-time":"2014-06-13T17:49:08Z","timestamp":1402681748000},"page":"862-868","source":"Crossref","is-referenced-by-count":30,"title":["Periodontal status and serum biomarkers levels in haemodialysis patients"],"prefix":"10.1111","volume":"41","author":[{"given":"Vandilson P.","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Postgraduate Dentistry Program Federal University of Maranh\u00e3o S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana A.","family":"Lib\u00e9rio","sequence":"additional","affiliation":[{"name":"Postgraduate Dentistry Program Federal University of Maranh\u00e3o S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda F.","family":"Lopes","sequence":"additional","affiliation":[{"name":"Postgraduate Dentistry Program Federal University of Maranh\u00e3o S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika B. F. A.","family":"Thomaz","sequence":"additional","affiliation":[{"name":"Department of Public Health Federal University of Maranh\u00e3o S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosane N. M.","family":"Guerra","sequence":"additional","affiliation":[{"name":"Laboratory of Immunophysiology Federal University of Maranh\u00e3o S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac S.","family":"Gomes\u2010Filho","sequence":"additional","affiliation":[{"name":"Department of Periodontics Feira de Santana State University Feira de Santana Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio L. 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