{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:11:39Z","timestamp":1791900699528,"version":"4.3.4"},"reference-count":12,"publisher":"Wiley","issue":"S16","license":[{"start":{"date-parts":[[2015,3,31]],"date-time":"2015-03-31T00:00:00Z","timestamp":1427760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004331","name":"Johnson & Johnson","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004331","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100004357","name":"Procter & Gamble","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004357","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Periodontitis is a ubiquitous and irreversible inflammatory condition and represents a significant public health burden. Severe periodontitis affects over 11% of adults, is a major cause of tooth loss impacting negatively upon speech, nutrition, quality of life and self\u2010esteem, and has systemic inflammatory consequences. Periodontitis is preventable and treatment leads to reduced rates of tooth loss and improved quality of life. However, successful treatment necessitates behaviour change in patients to address lifestyle risk factors (e.g. smoking) and, most importantly, to attain and sustain high standards of daily plaque removal, lifelong. While mechanical plaque removal remains the bedrock of successful periodontal disease management, in high\u2010risk patients it appears that the critical threshold for plaque accumulation to trigger periodontitis is low, and such patients may benefit from adjunctive agents for primary prevention of periodontitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aims of this working group were to systematically review the evidence for primary prevention of periodontitis by preventing gingivitis via four approaches: 1) the efficacy of mechanical self\u2010administered plaque control regimes; 2) the efficacy of self\u2010administered inter\u2010dental mechanical plaque control; 3) the efficacy of adjunctive chemical plaque control; and 4) anti\u2010inflammatory (sole or adjunctive) approaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two meta\u2010reviews (mechanical plaque removal) and two traditional systematic reviews (chemical plaque control\/anti\u2010inflammatory agents) formed the basis of this consensus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Data support the belief that professionally administered plaque control significantly improves gingival inflammation and lowers plaque scores, with some\u00a0evidence that reinforcement of oral hygiene provides further benefit. Re\u2010chargeable power toothbrushes provide small but statistically significant additional reductions in gingival inflammation and plaque levels. Flossing cannot be recommended other than for sites of gingival and periodontal health, where inter\u2010dental brushes (\n                      <jats:styled-content style=\"fixed-case\">IDB<\/jats:styled-content>\n                      s) will not pass through the interproximal area without trauma. Otherwise,\n                      <jats:styled-content style=\"fixed-case\">IDB<\/jats:styled-content>\n                      s are the device of choice for interproximal plaque removal. Use of local or systemic anti\u2010inflammatory agents in the management of gingivitis has no robust evidence base. We support the almost universal recommendations that all people should brush their teeth twice a day for at least 2\u00a0min. with fluoridated dentifrice. Expert opinion is that for periodontitis patients 2\u00a0min. is likely to be insufficient, especially when considering the need for additional use of inter\u2010dental cleaning devices. In patients with gingivitis once daily inter\u2010dental cleaning is recommended and the adjunctive use of chemical plaque control agents offers advantages in this group.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpe.12366","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T12:05:23Z","timestamp":1422533123000},"source":"Crossref","is-referenced-by-count":556,"title":["Primary prevention of periodontitis: managing gingivitis"],"prefix":"10.1111","volume":"42","author":[{"given":"Iain L. C.","family":"Chapple","sequence":"first","affiliation":[{"name":"Periodontal Research Group &amp; MRC Centre for Immune Regulation Birmingham Dental School Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fridus","family":"Van der Weijden","sequence":"additional","affiliation":[{"name":"ACTA Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"Doerfer","sequence":"additional","affiliation":[{"name":"University of Kiel Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Herrera","sequence":"additional","affiliation":[{"name":"University of Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lior","family":"Shapira","sequence":"additional","affiliation":[{"name":"Hadassah Medical Centers Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Polak","sequence":"additional","affiliation":[{"name":"Hadassah Medical Centers Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phoebus","family":"Madianos","sequence":"additional","affiliation":[{"name":"University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Louropoulou","sequence":"additional","affiliation":[{"name":"ACTA Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Machtei","sequence":"additional","affiliation":[{"name":"Ramban Medical Center Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikos","family":"Donos","sequence":"additional","affiliation":[{"name":"University College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Greenwell","sequence":"additional","affiliation":[{"name":"University of Louisville Louisville KY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari J.","family":"Van Winkelhoff","sequence":"additional","affiliation":[{"name":"University of Gr\u00f6nign Gr\u00f6nign The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahar","family":"Eren Kuru","sequence":"additional","affiliation":[{"name":"Yeditepe University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Arweiler","sequence":"additional","affiliation":[{"name":"University of Marburg Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim","family":"Teughels","sequence":"additional","affiliation":[{"name":"Catholic University Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Aimetti","sequence":"additional","affiliation":[{"name":"University of Turin Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Molina","sequence":"additional","affiliation":[{"name":"University of Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Montero","sequence":"additional","affiliation":[{"name":"University of Complutense Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Graziani","sequence":"additional","affiliation":[{"name":"University of Pisa Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,31]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"90","article-title":"The interdental bleeding index: a simplified procedure for monitoring gingival health","volume":"88","author":"Caton J. 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