{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T19:16:25Z","timestamp":1720293385283},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T00:00:00Z","timestamp":1433980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Clinic of Preventive Dentistry, Periodontology and Cariology, University of Zurich"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To assess the effect of concomitant subgingival rinsing with 10% <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\u2010iodine during subgingival instrumentation on the prevalence and magnitude of bacteraemia of oral origin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Subgingival instrumentation was performed with water or <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\u2010iodine rinse in patients with periodontitis. Prior to instrumentation, subjects gargled for 1\u00a0min with the allocated liquid. Pockets were then rinsed for 1\u00a0min and subgingivally instrumented with liquid\u2010cooled (water\/<jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\u2010iodine) ultrasonic scalers (1\u00a0min). Two minutes later, a blood sample from the arm vein was drawn using a lysis centrifugation blood culture system for quantitative microbiological analysis. Non\u2010parametric statistical tests were performed to assess differences in the prevalence and extent of bacteraemia between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 19 samples in each group, oral\u2010borne bacteraemia was detected in 10 of the control and 2 of the test samples. With an average of 3.0 [1; 5] colony forming units, significantly less bacteria and bacteraemia were found in the test group compared to the controls (12.2 [1; 46]) (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.003). Anaerobic bacteria were not found in the test group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Bacteraemia after subgingival instrumentation with concomitant <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\u2010iodine rinsing is reduced but not eliminated. Therefore, it might be recommended for patients at a high risk of endocarditis or infection of endoprostheses. However, preventive antibiotic treatment should not be omitted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12416","type":"journal-article","created":{"date-parts":[[2015,5,7]],"date-time":"2015-05-07T11:57:00Z","timestamp":1430999820000},"page":"632-639","source":"Crossref","is-referenced-by-count":14,"title":["Effect of application of a <scp>PVP<\/scp>\u2010iodine solution before and during subgingival ultrasonic instrumentation on post\u2010treatment bacteraemia: a randomized single\u2010centre placebo\u2010controlled clinical trial"],"prefix":"10.1111","volume":"42","author":[{"given":"Philipp","family":"Sahrmann","sequence":"first","affiliation":[{"name":"Clinic of Preventive Dentistry Cariology and Periodontology Center of Dental Medicine University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Manz","sequence":"additional","affiliation":[{"name":"Clinic of Preventive Dentistry Cariology and Periodontology Center of Dental Medicine University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Attin","sequence":"additional","affiliation":[{"name":"Clinic of Preventive Dentistry Cariology and Periodontology Center of Dental Medicine University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"Zbinden","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick R.","family":"Schmidlin","sequence":"additional","affiliation":[{"name":"Clinic of Preventive Dentistry Cariology and Periodontology Center of Dental Medicine University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0757.2002.290110.x"},{"key":"e_1_2_6_3_1","first-page":"299","article-title":"Tissue destruction in periodontitis: bacteria or cytokines fault?","volume":"36","author":"Bascones A.","year":"2005","journal-title":"Quintessence International"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2007.0025"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2009.12.001"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.01025.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.289.6457.1499"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.11.019"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.90B7.20417"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.32"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00924.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0765.2001.00011.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309019777"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2010.04.009"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00658.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2209\/tdcpublication.51.139"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.758524"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2007.0198"},{"key":"e_1_2_6_19_1","first-page":"119","article-title":"Principles of aetiology and pathogenesis governing the treatment of periodontal disease","volume":"33","author":"Loe H.","year":"1983","journal-title":"International Dental Journal"},{"key":"e_1_2_6_20_1","first-page":"27","article-title":"Systemic effects of periodontitis","volume":"18","author":"Loos B. 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