{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:28:52Z","timestamp":1788308932449,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T00:00:00Z","timestamp":1459209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Department of Periodontology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2016,4]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>To assess the effect of different stages of intervention on volatile sulphur compounds (VSC<\/jats:styled-content>s) of periodontitis patients with halitosis, before and after non\u2010surgical periodontal therapy.<\/jats:p><\/jats:sec>Material & Methods<\/jats:title>This\u00a0clinical trial\u00a0included 18 adults with chronic periodontitis and halitosis. After initial examination, patients received oral hygiene (OH<\/jats:styled-content>) instructions and tongue cleaner. One week later, non\u2010surgical periodontal therapy was completed within 48\u00a0h. Measurements were at baseline, 1\u00a0week after OH<\/jats:styled-content>, 1 and 6\u00a0weeks post therapy. These included simplified plaque index (sPlI<\/jats:styled-content>), probing pocket depth (PPD<\/jats:styled-content>), bleeding on probing (BoP), Winkel Tongue Coating Index (WTCI<\/jats:styled-content>), organoleptic scores (OLS<\/jats:styled-content>s) of nose and mouth air and VSC<\/jats:styled-content>s.<\/jats:p><\/jats:sec>Results<\/jats:title>sPlI<\/jats:styled-content>, BoP, WTCI<\/jats:styled-content>, OLS<\/jats:styled-content> of the mouth air and VSC<\/jats:styled-content>s showed significant differences (p<\/jats:italic>\u00a0<\u00a00.05), even after 1\u00a0week of OH<\/jats:styled-content>. A further significant decrease was determined 1\u00a0week after non\u2010surgical therapy for WTCI<\/jats:styled-content>, OLS<\/jats:styled-content> (nose and mouth air) and methyl mercaptan concentration. A significant decrease, 6\u00a0weeks post therapy, was observed for sPlI<\/jats:styled-content>, BoP, WTCI<\/jats:styled-content>, PPD<\/jats:styled-content>, OLS<\/jats:styled-content> of the nose and mouth air and VSC<\/jats:styled-content>s (p<\/jats:italic>\u00a0<\u00a00.05).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Oral hygiene and tongue cleaning improve the OLS<\/jats:styled-content>s of the mouth air and reduce VSC<\/jats:styled-content>s. Periodontal therapy further improves the OLS<\/jats:styled-content>s and reduces the concentration of VSC<\/jats:styled-content>s.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12521","type":"journal-article","created":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T17:04:48Z","timestamp":1454087088000},"page":"359-365","source":"Crossref","is-referenced-by-count":21,"title":["Changes of volatile sulphur compounds during therapy of a case series of patients with chronic periodontitis and halitosis"],"prefix":"10.1111","volume":"43","author":[{"given":"Avraam","family":"Iatropoulos","sequence":"first","affiliation":[{"name":"Department of Periodontology School of Dentistry National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasileios","family":"Panis","sequence":"additional","affiliation":[{"name":"Department of Periodontology School of Dentistry National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eirini","family":"Mela","sequence":"additional","affiliation":[{"name":"Department of Periodontology School of Dentistry National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodoros","family":"Stefaniotis","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis & Radiology School of Dentistry National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phoebus N.","family":"Madianos","sequence":"additional","affiliation":[{"name":"Department of Periodontology School of Dentistry National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Papaioannou","sequence":"additional","affiliation":[{"name":"Department of Preventive and Community Dentistry School of Dentistry National and Kapodistrian University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,29]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"156","article-title":"Halitosis: causes, diagnosis, and treatment","volume":"94","author":"Ayers K. 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