{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T16:35:25Z","timestamp":1771605325373,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T00:00:00Z","timestamp":1459209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Clinical Research Foundation (CRF) for the Promotion of Oral Health, Brienz, Switzerland"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to evaluate the role of a connective tissue graft (<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>) or a collagen matrix (<jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>) interpositioned between flaps and non\u2010shedding hard surfaces on wound stability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Sixty bone dehiscence defects were prepared in five Beagle dogs. Three treatments were performed in 12 sites per dog: (1) repositioned flaps were sutured onto instrumented dentin surfaces (control), (2) repositioning of flaps with an interpositioned <jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> and (3) repositioning of flaps with the application of a <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>. To allow postoperative healing with <jats:italic>n<\/jats:italic>\u00a0=\u00a05 for 1, 3, 7 and 14\u00a0days before evaluation, the sutures were removed, incision lines retraced and tensile forces applied to the flaps. The minimum magnitude of forces required to detach the flaps from the wound bed was recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After 1 week of healing, 6\u00a0N had to be applied to disrupt flaps from their wound bed in the <jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> group. In the control group, a similar magnitude of resistance was achieved after 2\u00a0weeks (6.1\u00a0N). Flap resistance to tearing was highest in the <jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> group (maximum 9.1\u00a0N) 2\u00a0weeks postoperatively. On the third postoperative day, the mean tearing forces of all groups differed significantly, displaying a 50% lower resistance to tearing in the <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content> compared to the <jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> group. In comparison, flap resistance to tearing forces established earlier and in higher magnitude in sites with an interpositioned <jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> than in flaps repositioned on dentin or <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Application of a <jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>, sutured to a non\u2010shedding hard surface, significantly increased flap resistance to tearing when applying disrupting forces compared to controls. A less pronounced effect was achieved by interpositioning of a <jats:styled-content style=\"fixed-case\">CM<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12526","type":"journal-article","created":{"date-parts":[[2016,2,5]],"date-time":"2016-02-05T02:06:37Z","timestamp":1454637997000},"page":"366-373","source":"Crossref","is-referenced-by-count":15,"title":["Interposition of a connective tissue graft or a collagen matrix to enhance wound stability \u2013 an experimental study in dogs"],"prefix":"10.1111","volume":"43","author":[{"given":"Rino","family":"Burkhardt","sequence":"first","affiliation":[{"name":"Prince Philip Dental Hospital The University of Hong Kong Hong Kong SAR China"},{"name":"University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Ruiz Magaz","sequence":"additional","affiliation":[{"name":"Universidad Internacional de Catalunya UIC Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph H.F.","family":"H\u00e4mmerle","sequence":"additional","affiliation":[{"name":"University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niklaus P.","family":"Lang","sequence":"additional","affiliation":[{"name":"Prince Philip Dental Hospital The University of Hong Kong Hong Kong SAR China"},{"name":"University of Zurich Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Research Group on Oral Soft Tissue Biology & Wound Healing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870070046008"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12357"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01829.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12193"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12182"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.110215"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.110382"},{"key":"e_1_2_5_10_1","first-page":"CD007161","article-title":"Root coverage procedures for the treatment of localised recession\u2010type defects","volume":"15","author":"Chambrone L.","year":"2009","journal-title":"Cochrane Database Systematic Reviews"},{"key":"e_1_2_5_11_1","first-page":"521","article-title":"A novel approach to root coverage: the pinhole surgical technique","volume":"32","author":"Chao J. 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