{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:10:43Z","timestamp":1789495843948,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T00:00:00Z","timestamp":1470787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study was to assess the clinical efficacy of coronally advanced flap (<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>) with or without connective tissue graft (<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>) for the treatment of multiple adjacent gingival recessions in the upper arch.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Thirty\u2010two patients with a total of 74 gingival recessions were randomly allocated to the two groups. Outcome measures, collected by a blind examiner, included complete root coverage (<jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content>), recession reduction (RecRed), keratinized tissue (<jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content>) gain, increase in gingival thickness (GT), patient satisfaction and root coverage esthetic score (<jats:styled-content style=\"fixed-case\">RES<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>An interaction between treatment and baseline <jats:styled-content style=\"fixed-case\">GT<\/jats:styled-content> was detected. At 1\u00a0year, <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> resulted in better outcomes in terms of <jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content> (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.0016) and RecRed (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001) than <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> alone at sites with thin gingiva (thickness\u00a0\u2264\u00a00.8\u00a0mm). No difference was found between <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> alone and <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> at sites with thick gingiva (&gt;0.8\u00a0mm). <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> resulted in higher aesthetic scores (<jats:styled-content style=\"fixed-case\">RES<\/jats:styled-content>) than <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> at sites with thick gingiva. <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> was associated with greater <jats:styled-content style=\"fixed-case\">KT<\/jats:styled-content> gain (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001) and greater post\u2010operative morbidity (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Connective tissue graft under <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> results in increased probability of <jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content> only at sites with thin baseline gingiva. <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> alone is associated with similar clinical outcomes and better aesthetics at sites with thick baseline gingiva.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12590","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T21:53:38Z","timestamp":1466632418000},"page":"849-856","source":"Crossref","is-referenced-by-count":111,"title":["Clinical efficacy of coronally advanced flap with or without connective tissue graft for the treatment of multiple adjacent gingival recessions in the aesthetic area: a randomized controlled clinical trial"],"prefix":"10.1111","volume":"43","author":[{"given":"Francesco","family":"Cairo","sequence":"first","affiliation":[{"name":"Section\u00a0of Periodontology Department of Surgery and Translational Medicine A.O.U. Careggi University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Cortellini","sequence":"additional","affiliation":[{"name":"Accademia Toscana di Ricerca Odontostomatologia (ATRO) Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Pilloni","sequence":"additional","affiliation":[{"name":"Section\u00a0of Periodontology University \u201cLa Sapienza\u201d of Rome Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Nieri","sequence":"additional","affiliation":[{"name":"Section\u00a0of Periodontology Department of Surgery and Translational Medicine A.O.U. Careggi University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Cincinelli","sequence":"additional","affiliation":[{"name":"Section\u00a0of Periodontology Department of Surgery and Translational Medicine A.O.U. 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