{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:51:26Z","timestamp":1783421486826,"version":"3.54.6"},"reference-count":45,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2016,9,16]],"date-time":"2016-09-16T00:00:00Z","timestamp":1473984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study was to perform a systematic review (<jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content>) of randomized controlled trials (<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s) to explore if periodontal plastic surgery procedures for the treatment of single and multiple gingival recessions (Rec) may improve aesthetics at patient and professional levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>In order to combine evidence from direct and indirect comparisons by different trials a Bayesian network meta\u2010analysis (<jats:styled-content style=\"fixed-case\">BNM<\/jats:styled-content>) was planned. A literature search on PubMed, Cochrane libraries, <jats:styled-content style=\"fixed-case\">EMBASE<\/jats:styled-content>, and hand\u2010searched journals until January 2016 was conducted to identify <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s presenting aesthetic outcomes after root coverage using standardized evaluations at patient and professional level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 16 <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s were selected in the <jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content>; three <jats:styled-content style=\"fixed-case\">RTC<\/jats:styled-content>s presenting professional aesthetic evaluation with Root coverage Aesthetic Score (<jats:styled-content style=\"fixed-case\">RES<\/jats:styled-content>) and three showing final self\u2010perception using the Visual Analogue Scale (<jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> Est) could be included in a <jats:styled-content style=\"fixed-case\">BNM<\/jats:styled-content> model. Coronally Advanced Flap plus Connective Tissue Graft (<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>) and <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0Acellular Dermal Matrix (<jats:styled-content style=\"fixed-case\">ADM<\/jats:styled-content>) and Autologous Fibroblasts (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) were associated with the best <jats:styled-content style=\"fixed-case\">RES<\/jats:styled-content> outcomes (best probability\u00a0=\u00a024% and 64%, respectively), while <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>\u00a0+\u00a0Enamel matrix Derivatives (<jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content>) obtained highest values of <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> Est score (best probability\u00a0=\u00a044% and 26%, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Periodontal Plastic Surgery (<jats:styled-content style=\"fixed-case\">PPS<\/jats:styled-content>) techniques applying grafts underneath <jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content> with or without the adding of <jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content> are associated with improved aesthetics assessed by final patient perception and <jats:styled-content style=\"fixed-case\">RES<\/jats:styled-content> as professional evaluation system.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12603","type":"journal-article","created":{"date-parts":[[2016,7,25]],"date-time":"2016-07-25T20:26:40Z","timestamp":1469478400000},"page":"965-975","source":"Crossref","is-referenced-by-count":71,"title":["Root coverage procedures improve patient aesthetics. A systematic review and Bayesian network meta\u2010analysis"],"prefix":"10.1111","volume":"43","author":[{"given":"Francesco","family":"Cairo","sequence":"first","affiliation":[{"name":"Section\u00a0of Periodontology Department of Surgery and Translational Medicine University of Florence Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Pagliaro","sequence":"additional","affiliation":[{"name":"Private Practice Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9945-0666","authenticated-orcid":false,"given":"Jacopo","family":"Buti","sequence":"additional","affiliation":[{"name":"School of Dentistry University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michela","family":"Baccini","sequence":"additional","affiliation":[{"name":"Department of Statistics, Informatics and Applications \u201cG. 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