{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T13:36:00Z","timestamp":1775396160586,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T00:00:00Z","timestamp":1475193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the effect of cigarette smoking on periodontal health at patient, tooth, and site levels following supportive therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Eighty chronic periodontitis patients, 40 smokers and 40 non\u2010smokers, were recruited to a single\u2010arm clinical trial. Periodontal examinations were performed at baseline (T0), 3\u00a0months following active periodontal therapy (T1), and 12\u00a0months following supportive periodontal therapy (T2). Smoking status was validated measuring serum cotinine levels. Probing depth (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>)\u00a0\u2265\u00a05\u00a0mm with bleeding on probing (BoP) was defined as the primary outcome. Logistic regression analyses adjusted for clustered observations of patients, teeth, and sites and mixed effects models were employed to analyse the data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All clinical parameters improved from T0 to T2 (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001), whereas <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>, bleeding index (<jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content>), and plaque index (<jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>) increased from T1 to T2 in smokers and non\u2010smokers (<jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). An overall negative effect of smoking was revealed at T2 (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a02.78, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.49, 5.18, <jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001), with the most pronounced effect at maxillary single\u2010rooted teeth (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a05.08, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 2.01, 12.78, <jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). At the patient level, less variation in treatment outcome was detected within smokers (<jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>\u00a0=\u00a00.137) compared with non\u2010smokers (<jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>\u00a0=\u00a00.051).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Smoking has a negative effect on periodontal health following 12\u00a0months of supportive therapy, in particular at maxillary single\u2010rooted teeth.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12619","type":"journal-article","created":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T08:22:53Z","timestamp":1472026973000},"page":"1086-1093","source":"Crossref","is-referenced-by-count":27,"title":["Site\u2010specific treatment outcome in smokers following 12\u00a0months of supportive periodontal therapy"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8592-7467","authenticated-orcid":false,"given":"Dagmar F.","family":"Bun\u00e6s","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Dentistry Department of Clinical Dentistry University of Bergen Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stein Atle","family":"Lie","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry Department of Clinical Dentistry University of Bergen Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Nordrehaug","family":"\u00c5str\u00f8m","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry Department of Clinical Dentistry University of Bergen Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamal","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry Department of Clinical Dentistry University of Bergen Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Knut N.","family":"Leknes","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry Department of Clinical Dentistry University of Bergen Bergen Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,30]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"229","article-title":"Problems and pro\u2010posals for recording gingivitis and plaque","volume":"25","author":"Ainamo J.","year":"1975","journal-title":"International Dental Journal"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107BOR-2014.vol28.0058"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1981.tb02039.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00563.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028007680.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12462"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.290815.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1994.tb00718.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.3.398"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.2.145"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.1.16"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01223.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01184.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070296"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2014.140048"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028004283.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwk066"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000169"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2002.290812.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.7.675"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.3.433"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1979.50.5.225"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb01187.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1990.tb01059.x"},{"key":"e_1_2_6_27_1","first-page":"7","article-title":"Periodontal risk assessment (PRA) for patients in supportive periodontal therapy (SPT)","volume":"1","author":"Lang N. P.","year":"2003","journal-title":"Oral Health & Preventive Dentistry"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1984.tb00902.x"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1984.tb01344.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb02091.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01245.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01508.x"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.12.731"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.1.38"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060264"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016358509046515"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00779.x"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00659.x"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb02247.x"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12242"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12344"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01723.x"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028003241.x"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12419"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2001.280801.x"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051x.2004.00588.x"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00822.x"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028010955.x"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.4.311"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjcpe.12619","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjcpe.12619","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.12619","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jcpe.12619","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.12619","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T04:52:31Z","timestamp":1700628751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.12619"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,30]]},"references-count":48,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1111\/jcpe.12619"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.12619","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,30]]}}}