{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:06:31Z","timestamp":1792757191239,"version":"4.5.0"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T00:00:00Z","timestamp":1497916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004348","name":"Stockholms L\u00e4ns Landsting","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To relate cardiac biomarkers, such as cystatin C and growth differentiation factor\u201015 (<jats:styled-content style=\"fixed-case\">GDF<\/jats:styled-content>\u201015) in saliva to myocardial infarction (<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content>) and to periodontal status, and to investigate the relation between salivary and plasma cardiac biomarkers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Two hundred patients with <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> admitted to coronary care units and 200 matched controls without <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> were included. Dental examination and collection of blood and saliva samples was performed 6\u201310\u00a0weeks after the <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> for patients and in close proximity thereafter for controls. Analysing methods: <jats:styled-content style=\"fixed-case\">ARCHITECT<\/jats:styled-content> i4000<jats:styled-content style=\"fixed-case\">SR<\/jats:styled-content>, Immulite 2000 <jats:styled-content style=\"fixed-case\">XP<\/jats:styled-content>i or <jats:styled-content style=\"fixed-case\">ELISA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age was 62\u00a0\u00b1\u00a08\u00a0years and 84% were male. Total probing pocket depth, fibrinogen, white blood cell counts and HbA1c were higher in patients than controls. <jats:styled-content style=\"fixed-case\">GDF<\/jats:styled-content>\u201015 levels correlated with most of the included clinical variables in both study groups. No correlation was found between plasma and saliva levels of cystatin C or <jats:styled-content style=\"fixed-case\">GDF<\/jats:styled-content>\u201015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Salivary cystatin C and <jats:styled-content style=\"fixed-case\">GDF<\/jats:styled-content>\u201015 could not differentiate between <jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content> patients and controls.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12740","type":"journal-article","created":{"date-parts":[[2017,4,28]],"date-time":"2017-04-28T16:44:42Z","timestamp":1493397882000},"page":"692-699","source":"Crossref","is-referenced-by-count":13,"title":["Saliva and plasma levels of cardiac\u2010related biomarkers in post\u2010myocardial infarction 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