{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T21:16:05Z","timestamp":1790198165147,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T00:00:00Z","timestamp":1503619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To systematically review the literature in order to investigate a potential association between periodontitis and halitosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Electronic searches were performed in four different databases: PubMed, Scopus, Web of Science and Scielo. Population\u2010based observational studies that tested the association between periodontitis and halitosis were included. Additionally, meta\u2010analysis, meta\u2010regression and subgroup analyses were performed to synthesize the evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1,107 articles were identified in electronic searches; out of which, five were included within the meta\u2010analysis. Pooled estimates revealed that individuals with periodontitis presented 3.16 times higher odds (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.16; 95% CI: 1.12\u20138.95) of having halitosis. Meta\u2010regression and subgroups analyses showed that criteria used for halitosis and periodontitis assessment explained nearly 45% and 24% of heterogeneity between studies, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Positive association between periodontitis and halitosis was found in pooled results of population\u2010based observational studies. However, this evidence is derived from cross\u2010sectional studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12786","type":"journal-article","created":{"date-parts":[[2017,7,27]],"date-time":"2017-07-27T15:53:01Z","timestamp":1501170781000},"page":"1003-1009","source":"Crossref","is-referenced-by-count":49,"title":["Is periodontitis associated with halitosis? A systematic review and meta\u2010regression analysis"],"prefix":"10.1111","volume":"44","author":[{"given":"Manuela F.","family":"Silva","sequence":"first","affiliation":[{"name":"Graduate Program in Dentistry Federal University of Pelotas  Pelotas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana G.","family":"Cademartori","sequence":"additional","affiliation":[{"name":"Graduate Program in Dentistry Federal University of Pelotas  Pelotas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8053-4517","authenticated-orcid":false,"given":"F\u00e1bio R. 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