{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T03:17:11Z","timestamp":1779247031083,"version":"3.51.4"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T00:00:00Z","timestamp":1512432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Nobel Biocare Services AG","award":["2012-1135"],"award-info":[{"award-number":["2012-1135"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the effect of connective tissue grafting on the mid\u2010buccal mucosal level (<jats:styled-content style=\"fixed-case\">MBML<\/jats:styled-content>) of immediately placed and provisionalized single implants in the maxillofacial aesthetic zone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Sixty patients with a failing tooth were provided with an immediately placed and provisionalized implant. During implant placement, patients randomly received either a connective tissue graft from the maxillary tuberosity (<jats:italic>n<\/jats:italic>\u00a0=\u00a030, test group) or no graft (<jats:italic>n<\/jats:italic>\u00a0=\u00a030, control group). Follow\u2010up visits were at one (T<jats:sub>1<\/jats:sub>) and twelve months (T<jats:sub>12<\/jats:sub>) after final crown placement. The primary outcome measure was any change in <jats:styled-content style=\"fixed-case\">MBML<\/jats:styled-content> compared to the pre\u2010operative situation. In addition, gingival biotype, aesthetics (using the Pink Esthetic Score\u2013White Esthetic Score), marginal bone level, soft tissue peri\u2010implant parameters and patient satisfaction were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean <jats:styled-content style=\"fixed-case\">MBML<\/jats:styled-content> change at T<jats:sub>12<\/jats:sub> was \u22120.5\u00a0\u00b1\u00a01.1\u00a0mm in the control group and 0.1\u00a0\u00b1\u00a00.8\u00a0mm in the test group (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.03). No significant differences regarding other outcome variables were observed, neither was gingival biotype associated with a gain or loss in <jats:styled-content style=\"fixed-case\">MBML<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This one\u2010year study shows that connective tissue grafting in single, immediately placed and provisionalized implants leads to less recession of the peri\u2010implant soft tissue at the mid\u2010buccal aspect, irrespective of the gingival biotype (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.trialregister.nl\">www.trialregister.nl<\/jats:ext-link>: <jats:styled-content style=\"fixed-case\">TC<\/jats:styled-content>3815).<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12820","type":"journal-article","created":{"date-parts":[[2017,9,23]],"date-time":"2017-09-23T15:03:05Z","timestamp":1506178985000},"page":"253-264","source":"Crossref","is-referenced-by-count":104,"title":["Effect of connective tissue grafting on peri\u2010implant tissue in single immediate implant sites: A <scp>RCT<\/scp>"],"prefix":"10.1111","volume":"45","author":[{"given":"Elise G.","family":"Zuiderveld","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henny J. A.","family":"Meijer","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen University Medical Center Groningen  Groningen The Netherlands"},{"name":"Department of Implant Dentistry Dental School University of Groningen University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurens","family":"den Hartog","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjan","family":"Vissink","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerry M.","family":"Raghoebar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University of Groningen University Medical Center Groningen  Groningen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,5]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"11","article-title":"The long\u2010term efficacy of currently used dental implants: A review and proposed criteria of success","volume":"1","author":"Albrektsson T.","year":"1986","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01317.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080435"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02253.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02516.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.2326"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2014suppl.g3.3"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-10-00110"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12571"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2012.01888.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12074"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2007.01413.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.41.4.1149"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.140394"},{"key":"e_1_2_9_16_1","first-page":"326","article-title":"Regeneration of gingival papillae after single\u2010implant treatment","volume":"17","author":"Jemt T.","year":"1997","journal-title":"The International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_9_17_1","first-page":"237","article-title":"Gingival biotype assessment in the esthetic zone: Visual versus direct measurement","volume":"30","author":"Kan J. 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