{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:15:56Z","timestamp":1788905756078,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T00:00:00Z","timestamp":1516320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009787","name":"Scottish Environment Protection Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005774","name":"Universitat de Barcelona","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Periodontitis and diabetes are highly prevalent conditions whose association has long been recognized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effect of non\u2010surgical periodontal treatment on serum HbA1c (haemoglobin A1c or glycated haemoglobin) levels in patients with type 2 diabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Research Design and Methods<\/jats:title><jats:p>This was a 6\u2010month, single\u2010masked, randomized clinical trial based on 90 patients (HbA1c: 7.7% (61\u00a0mmol\/mol)\u00a0\u00b1\u00a01.13%) who were randomly assigned to either the treatment group (oral hygiene instructions\u00a0+\u00a0scaling and root planing using ultrasound and Gracey curettes) or the control group (oral hygiene instructions\u00a0+\u00a0supragingival removal of plaque and calculus using ultrasound). Pocket depth, gingival index, and plaque index were assessed at baseline and after 3 and 6\u00a0months together with determinations of fasting plasma glucose, HbA1c, and bacterial counts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Treatment significantly improved the periodontal and metabolic parameters (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.05), whereas in the control group no improvement was observed. These results were consistent with the bacteriological results in most but not all cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Non\u2010surgical periodontal treatment resulted in a better glycaemic status of type 2 diabetes patients and demonstrated the importance of oral health in their general health.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12858","type":"journal-article","created":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T05:36:38Z","timestamp":1513661798000},"page":"345-353","source":"Crossref","is-referenced-by-count":101,"title":["Benefits of non\u2010surgical periodontal treatment in patients with type 2 diabetes mellitus and chronic periodontitis: A randomized controlled trial"],"prefix":"10.1111","volume":"45","author":[{"given":"Elisabet","family":"Mauri\u2010Obradors","sequence":"first","affiliation":[{"name":"Department of Dentistry Dental School University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Merlos","sequence":"additional","affiliation":[{"name":"Department of Pathology and Experimental Therapeutics Medical School IDIBELL\u2010University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Estrugo\u2010Devesa","sequence":"additional","affiliation":[{"name":"Department of Dentistry Dental School University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enric","family":"Jan\u00e9\u2010Salas","sequence":"additional","affiliation":[{"name":"Department of Dentistry Dental School University of Barcelona Barcelona Spain"},{"name":"Oral Medicine Unit Department of Dentistry Faculty of Medicine and Health Sciences (Dental School) and Dental Hospital Barcelona University (University of Barcelona) and Health and Masticatory System Group (Bellvitge Biomedical Research, Institute) IDIBELL Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3536-4109","authenticated-orcid":false,"given":"Jos\u00e9","family":"L\u00f3pez\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Dentistry Dental School University of Barcelona Barcelona Spain"},{"name":"Oral Medicine Unit Department of Dentistry Faculty of Medicine and Health Sciences (Dental School) and Dental Hospital Barcelona University (University of Barcelona) and Health and Masticatory System Group (Bellvitge Biomedical Research, Institute) IDIBELL Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2073-3386","authenticated-orcid":false,"given":"Miguel","family":"Vi\u00f1as","sequence":"additional","affiliation":[{"name":"Department of Pathology and Experimental Therapeutics Medical School IDIBELL\u2010University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,19]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"77","article-title":"Type 2 diabetes mellitus and periodontal disease severity","volume":"12","author":"Al\u2010Khabbaz A. 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