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Tooth loss could reflect the accumulation of oral local inflammation, implying that number of missing teeth may associate with <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content>. This study evaluated the association between missing teeth and presence of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> in a general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A cross\u2010sectional study of 24,470 adults was carried out from the Tianjin Chronic Low\u2010grade Systemic Inflammation and Health Cohort Study. The self\u2010reported number of missing teeth (excluding third molars) was recorded and classified into four categories: 0, 1\u20132, 3\u20135, and \u22656. The <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> was diagnosed by the liver ultrasonography. Associations were analysed by adjusted multivariable logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The multivariable\u2010adjusted odds ratios (95% confidence interval) of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> across the categories of missing teeth were as follows: in males, 1.00 (reference), 1.04 (0.93\u20131.16), 1.06 (0.90\u20131.24), and 1.40 (1.09\u20131.81) (<jats:italic>p<\/jats:italic> for trend\u00a0=\u00a00.04); in females, 1.00 (reference), 0.98 (0.83\u20131.15), 1.11 (0.90\u20131.37), and 1.07 (0.77\u20131.48) (<jats:italic>p<\/jats:italic> for trend\u00a0=\u00a00.45).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The number of missing teeth was associated with a higher presence of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> in males but not females.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.12929","type":"journal-article","created":{"date-parts":[[2018,5,20]],"date-time":"2018-05-20T01:17:30Z","timestamp":1526779050000},"page":"941-951","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The association between missing teeth and non\u2010alcoholic fatty liver disease in adults"],"prefix":"10.1111","volume":"45","author":[{"given":"Feng","family":"Qiao","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery School and Hospital of Stomatology Tianjin Medical University  Tianjin China"},{"name":"Nutritional Epidemiology Institute and School of Public Health Tianjin Medical University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiyu","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery School and Hospital of Stomatology Tianjin 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