{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:08:26Z","timestamp":1789474106771,"version":"build-2803163510"},"reference-count":45,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,11,25]],"date-time":"2018-11-25T00:00:00Z","timestamp":1543104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI16\/00301"],"award-info":[{"award-number":["PI16\/00301"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The effect of dietary weight loss intervention on periodontal therapy is unknown. Therefore, we aimed to evaluate whether weight loss improves the response of obese subjects to non\u2010surgical periodontal treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This interventional study in obese patients was conducted at the University Hospital Dr. Peset (Valencia, Spain). Patients were divided into two groups with and without dietary therapy. All participants received non\u2010surgical periodontal treatment. Periodontal, anthropometric and biochemical parameters were assessed at baseline and 12\u00a0weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 78 patients were re\u2010evaluated after intervention. All periodontal parameters improved in both groups after periodontal treatment, but the reductions in mean probing depth (PD) (0.23\u00a0mm vs. 0.12\u00a0mm) and in percentage of sites with PD 4\u20135\u00a0mm (10.4% vs. 5.89%) were significantly higher in the dietary group. Additionally, complement component 3 (C3) and tumour necrosis factor alpha (TNF\u03b1) decreased in the dietary group after intervention. Percentage of change in mean PD correlated with change in C3 (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.233, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.043), and percentage of change in sites with PD 4\u20135\u00a0mm correlated with change in TNF\u03b1 (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.414, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.012).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study suggests that dietary weight loss intervention causes a greater reduction in systemic inflammation, which may enhance the response to periodontal treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13030","type":"journal-article","created":{"date-parts":[[2018,10,26]],"date-time":"2018-10-26T12:22:33Z","timestamp":1540556553000},"page":"1448-1457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Dietary therapy and non\u2010surgical periodontal treatment in obese patients with chronic periodontitis"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1965-7099","authenticated-orcid":false,"given":"Mayte","family":"Martinez\u2010Herrera","sequence":"first","affiliation":[{"name":"Service of Stomatology University Hospital Doctor Peset\u2010FISABIO  Valencia Spain"},{"name":"Department of Stomatology University of Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"L\u00f3pez\u2010Dom\u00e8nech","sequence":"additional","affiliation":[{"name":"Service of Endocrinology and Nutrition University Hospital Doctor Peset\u2010FISABIO  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Javier","family":"Silvestre","sequence":"additional","affiliation":[{"name":"Service of Stomatology University Hospital Doctor Peset\u2010FISABIO  Valencia Spain"},{"name":"Department of Stomatology University of Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Silvestre\u2010Rangil","sequence":"additional","affiliation":[{"name":"Department of Stomatology University of Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia","family":"Ba\u00f1uls","sequence":"additional","affiliation":[{"name":"Service of Endocrinology and Nutrition University Hospital Doctor Peset\u2010FISABIO  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Hern\u00e1ndez\u2010Mijares","sequence":"additional","affiliation":[{"name":"Service of Endocrinology and Nutrition University Hospital Doctor Peset\u2010FISABIO  Valencia Spain"},{"name":"Department of Medicine University of Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2923-6546","authenticated-orcid":false,"given":"Milagros","family":"Rocha","sequence":"additional","affiliation":[{"name":"Service of Endocrinology and Nutrition University Hospital Doctor Peset\u2010FISABIO  Valencia Spain"},{"name":"CIBER CB06\/04\/0071 Research Group CIBER Hepatic and Digestive Diseases University of Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.110646"},{"key":"e_1_2_9_3_1","first-page":"309","article-title":"Effect of periodontal treatment on serum C\u2010reactive protein level in obese and normal\u2010weight women affected with chronic periodontitis","volume":"33","author":"Al\u2010Zahrani M. 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