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The included studies had at least two groups of patients: chronic periodontitis only (P) or both diabetes and chronic periodontitis (<jats:styled-content style=\"fixed-case\">DMP<\/jats:styled-content>). Outcomes of interest included the difference between the two groups in probing depth (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>) reduction and clinical attachment level (<jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content>) gain following non\u2010surgical periodontal therapy. Meta\u2010regression was conducted to evaluate the correlation between the outcomes of interest and contributing factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 12 studies with a follow\u2010up period up to 6\u00a0months were included. There was no significant difference in <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> reduction (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.55) or <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> gain (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.65) between the two groups. A positive association between <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> reduction and baseline <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> difference (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.03), and a negative association between <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> reduction and age (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.04) were found. The level of HbA1c at baseline did not significantly affect the difference in <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> reduction (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.39) or <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> gain (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.44) between two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Recognizing the study's limitations, we conclude that diabetes mellitus (HbA1c\u00a0\u2264\u00a08.5%) does not appear to significantly affect short\u2010term clinical periodontal outcomes of non\u2010surgical periodontal treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13044","type":"journal-article","created":{"date-parts":[[2018,12,8]],"date-time":"2018-12-08T08:00:59Z","timestamp":1544256059000},"page":"206-217","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Impact of diabetes on clinical periodontal outcomes following non\u2010surgical periodontal therapy"],"prefix":"10.1111","volume":"46","author":[{"given":"Yung\u2010Ting","family":"Hsu","sequence":"first","affiliation":[{"name":"Division of Graduate Periodontology Department of Graduate Studies University of Detroit Mercy School of Dentistry  Detroit Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Nair","sequence":"additional","affiliation":[{"name":"University of Texas at Austin  Austin Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikola","family":"Angelov","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Dental Hygiene University of Texas Health Science Center at Houston  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evanthia","family":"Lalla","sequence":"additional","affiliation":[{"name":"Division of Periodontics Columbia University College of Dental Medicine  New York City New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7812-5637","authenticated-orcid":false,"given":"Chun\u2010Teh","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Dental Hygiene University of Texas Health Science Center at Houston  Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,1,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2015.12.005"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1982.tb02038.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.114953"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.3.418"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2013.1340011"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02417.x"},{"issue":"8","key":"e_1_2_9_8_1","first-page":"671","article-title":"Clinical and metabolic evaluation of one\u2010stage, full\u2010mouth, ultrasonic debridement as a therapeutic approach for uncontrolled type 2 diabetic patients with periodontitis","volume":"43","author":"Cirano F. 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