{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T20:16:02Z","timestamp":1760300162113,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T00:00:00Z","timestamp":1553731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007619","name":"Osteology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the influence of autoclavation on the efficacy of extracted tooth roots (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>) used for vertical alveolar ridge augmentation and two\u2010stage osseointegration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Maxillary premolars were randomly assigned to either autoclavation (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010A) or were left untreated (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C) and used as block grafts for vertical alveolar ridge augmentation in both lower quadrants (<jats:italic>n<\/jats:italic>\u00a0=\u00a04 beagle dogs). At 12\u00a0weeks, titanium implants were inserted and left to heal for 3\u00a0weeks. Histological analyses considered vertical bone gain (<jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">BC<\/jats:styled-content>), augmented area (<jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>) and bone\u2010to\u2010implant contact (<jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content>) at vestibular (v) and oral (o) aspects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C and <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010A (exposures <jats:italic>n<\/jats:italic>\u00a0=\u00a03) grafts were associated with a replacement resorption and marked vertical bone gain. Median <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">BC<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C: 1.45 [v] to 1.62\u00a0mm [o] versus <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010A: 0.97 [v] to 1.79\u00a0mm [o]) and <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C: 0.64 [v] to 2.36\u00a0mm<jats:sup>2<\/jats:sup> [o] versus <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010A: 0.22 [v] to 2.36\u00a0mm<jats:sup>2<\/jats:sup> [o]) values were comparable in both groups. V <jats:styled-content style=\"fixed-case\">BIC<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C: 49.32 [v] to 52.97% [o] versus <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010A: 25.34 [v] to 46.11% [o]) values were significantly higher in the <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C and <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010A grafts equally supported vertical alveolar ridge augmentation; however, osseointegration was partially facilitated in the <jats:styled-content style=\"fixed-case\">TR<\/jats:styled-content>\u2010C group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13090","type":"journal-article","created":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T18:12:31Z","timestamp":1550772751000},"page":"502-509","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Influence of autoclavation on the efficacy of extracted tooth roots used for vertical alveolar ridge augmentation"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5515-227X","authenticated-orcid":false,"given":"Frank","family":"Schwarz","sequence":"first","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University  Frankfurt Germany"},{"name":"Department of Oral Surgery Universit\u00e4tsklinikum D\u00fcsseldorf  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilja","family":"Mihatovic","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery Universit\u00e4tsklinikum D\u00fcsseldorf  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingela","family":"Popal\u2010Jensen","sequence":"additional","affiliation":[{"name":"Private Practice  Lampertheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puria","family":"Parvini","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University  Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Sader","sequence":"additional","affiliation":[{"name":"Department for Oral, Cranio\u2010Maxillofacial and Facial Plastic Surgery Medical Center of the Goethe University Frankfurt  Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12803"},{"issue":"12","key":"e_1_2_8_3_1","first-page":"502","article-title":"Preclinical in vivo research in implant dentistry Consensus of the eighth European workshop on periodontology","volume":"39","author":"Berglundh T.","year":"2012","journal-title":"Journal of Clinical Periodontology"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.5125\/jkaoms.2013.39.3.103"},{"key":"e_1_2_8_5_1","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0255-0857(21)02532-9","article-title":"Sterilisation of extracted human teeth for educational use","volume":"23","author":"Kumar M.","year":"2005","journal-title":"Indian Journal of Medical Microbiology"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092240206"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.21815\/JDE.018.012"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v013a01"},{"key":"e_1_2_8_9_1","first-page":"243","article-title":"Vertical ridge augmentation using xenogenous bone blocks: A histomorphometric study in dogs","volume":"24","author":"Rothamel D.","year":"2009","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_8_10_1","first-page":"502","volume-title":"Methods of calcified tissue preparation","author":"Schenk R. 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