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Randomized controlled trials (<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s) following \u22652\u00a0years were selected. Primary outcomes were complete root coverage (<jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content>) and mean root coverage (<jats:styled-content style=\"fixed-case\">MRC<\/jats:styled-content>). Secondary outcomes were width of keratinized tissue (<jats:styled-content style=\"fixed-case\">KTW<\/jats:styled-content>) and patient\u2010centred parameters. Meta\u2010analysis was conducted when possible.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of fifteen<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s were included. The results demonstrated significantly higher<jats:styled-content style=\"fixed-case\">MRC<\/jats:styled-content>in short\u2010term than long\u2010term after coronally advanced flap (<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>; 7.29%,<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.006). When<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>combined with connective tissue graft (<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>), no significant difference was observed in<jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content>or<jats:styled-content style=\"fixed-case\">MRC<\/jats:styled-content>for short\u2010term versus long\u2010term (1.00,<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.97; 2.35%,<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.09), and it resulted in better long\u2010term efficacy than<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>alone in terms of<jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content>(0.69,<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0006) and<jats:styled-content style=\"fixed-case\">KTW<\/jats:styled-content>(\u22120.63\u00a0mm,<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.04). For<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>plus enamel matrix derivative, the meta\u2010analysis showed no significant difference between the short\u2010term and long\u2010term results of<jats:styled-content style=\"fixed-case\">CRC<\/jats:styled-content>(1.26,<jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.21).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>alone could result in decreased postoperative percentage of root coverage with time.<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">CTG<\/jats:styled-content>could maintain long\u2010term stability and result in better root coverage outcomes than<jats:styled-content style=\"fixed-case\">CAF<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13106","type":"journal-article","created":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T04:37:11Z","timestamp":1555130231000},"page":"572-585","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Long\u2010term stability of root coverage procedures for single gingival recessions: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"46","author":[{"given":"Anna","family":"Dai","sequence":"first","affiliation":[{"name":"Department of Periodontology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2010Ping","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Periodontology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6147-1787","authenticated-orcid":false,"given":"Pei\u2010Hui","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Periodontology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0620-8844","authenticated-orcid":false,"given":"Li\u2010Li","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Periodontology The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,29]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"E304","article-title":"A comparative study of the long term results of root coverage with connective tissue graft or enamel matrix protein: 24\u2010month results","volume":"14","author":"Abolfazli N.","year":"2009","journal-title":"Medicina Oral Patologia Oral y Cirugia Bucal"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12377"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.6.989"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12333"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080498"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12028"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12186"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12182"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12603"},{"key":"e_1_2_7_11_1","first-page":"CD007161","article-title":"Root coverage procedures for treating localised and multiple recession\u2010type defects","volume":"10","author":"Chambrone L.","year":"2018","journal-title":"Cochrane Database Systematic Review"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090540"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.130674"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2011.00434.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01346.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00969.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00831.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12328"},{"key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"439","DOI":"10.4103\/jisp.jisp_222_17","article-title":"Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review","volume":"21","author":"Gallagher S. 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