{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:46:05Z","timestamp":1791549965526,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"S21","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Geistlich Pharma AG"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The transition from a tooth requiring extraction to its replacement (with a dental implant) requires a series of clinical decisions related to timing, approach, materials, cost\u2010effectiveness and the assessment of potential harm and patient preference. This workshop focused on the formulation of evidence\u2010based consensus statements and clinical recommendations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Four systematic reviews covering the areas of alveolar ridge preservation\/bone grafting, immediate early and delayed implant placement and alveolar bone augmentation at the time of implant placement in a healed ridge formed the basis of the deliberations. The level of evidence supporting each consensus statement and its strength was described using a modification of the <jats:styled-content style=\"fixed-case\">GRADE<\/jats:styled-content> tool.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The evidence base for each of the relevant topics was assessed and summarized in 23 consensus statements and 12 specific clinical recommendations. The group emphasized that the evidence base mostly relates to single tooth extraction\/replacement; hence, external validity\/applicability to multiple extractions requires careful consideration. The group identified six considerations that should assist clinicians in clinical decision\u2010making: presence of infection, inability to achieve primary stability in the restoratively driven position, presence of a damaged alveolus, periodontal phenotype, aesthetic demands and systemic conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A substantial and expanding evidence base is available to assist clinicians with clinical decision\u2010making related to the transition from a tooth requiring extraction to its replacement with a dental implant. More high\u2010quality research is needed for the development of evidence\u2010based clinical guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13131","type":"journal-article","created":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T09:26:49Z","timestamp":1560936409000},"page":"183-194","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":207,"title":["Management of the extraction socket and timing of implant placement: Consensus report and clinical recommendations of group 3 of the <scp>XV<\/scp> European Workshop in Periodontology"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2743-0137","authenticated-orcid":false,"given":"Maurizio S.","family":"Tonetti","sequence":"first","affiliation":[{"name":"Division of Periodontology and Implant Dentistry Faculty of Dentistry University of Hong Kong  Hong Kong China"},{"name":"European Research Group on Periodontology  Genova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald E.","family":"Jung","sequence":"additional","affiliation":[{"name":"Clinic of Fixed and Removable Prosthodontics and Dental Material Science University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5763-0201","authenticated-orcid":false,"given":"Gustavo","family":"Avila\u2010Ortiz","sequence":"additional","affiliation":[{"name":"Department of Periodontics The University of Iowa  Iowa City Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Blanco","sequence":"additional","affiliation":[{"name":"Department of Surgery and Medical\u2010Surgical Specialties (Dentistry area) Unit of Periodontology University of Santiago de Compostela  Santiago Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5042-2875","authenticated-orcid":false,"given":"Jan","family":"Cosyn","sequence":"additional","affiliation":[{"name":"Department of Dentistry University of Ghent  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Fickl","sequence":"additional","affiliation":[{"name":"Division of Periodontology University of W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Figuero","sequence":"additional","affiliation":[{"name":"ETEP (Etiology and Therapy of Periodontal Diseases) Research Group Department of Dental Clinic Specialties Faculty of Dentistry University Complutense  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moshe","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Department of Periodontology Hebrew University  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8780-7306","authenticated-orcid":false,"given":"Filippo","family":"Graziani","sequence":"additional","affiliation":[{"name":"Sub\u2010Unit of Periodontology, Halitosis and Periodontal Medicine Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5990-5723","authenticated-orcid":false,"given":"Phoebus","family":"Madianos","sequence":"additional","affiliation":[{"name":"Department of Periodontology Kapodistrian University  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Molina","sequence":"additional","affiliation":[{"name":"ETEP (Etiology and Therapy of Periodontal Diseases) Research Group Department of Dental Clinic Specialties Faculty of Dentistry University Complutense  Madrid 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