{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:56:11Z","timestamp":1787586971614,"version":"build-2736575974"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,10,22]],"date-time":"2019-10-22T00:00:00Z","timestamp":1571702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to determine whether the combined connective tissue graft (CTG) with injectable platelet\u2010rich fibrin (i\u2010PRF) with coronally advanced flap (CAF) improved root coverage of deep Miller Class I or II gingival recessions compared with CTG alone with CAF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Seventy\u2010two patients with Miller class I and II gingival recessions were enrolled. Thirty\u2010six patients were randomly assigned to the test group (CAF+CTG+i\u2010PRF [700\u00a0rpm for 3\u00a0min]) or control group (CAF+CTG). Clinical evaluations were made at 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6\u00a0months, complete root coverage was obtained at 88% of the sites treated with CAF+CTG+i\u2010PRF and 80% of the sites treated with CAF+CTG. Difference between the two groups was not statistically significant. At 6\u00a0months, the recession depth (RD) reduction and increase in keratinized tissue height (KTH) of the test sites were significantly better compared with the control sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>According to the results, the addition of i\u2010PRF to the CAF+CTG treatment showed further development in terms of increasing the KTH and decreasing RD. However, this single trial is not sufficient to advocate the true clinical effect of i\u2010PRF on recession treatment with CAF+CTG and additional trials are needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13193","type":"journal-article","created":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T20:54:30Z","timestamp":1568408070000},"page":"72-80","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Clinical evaluation of injectable platelet\u2010rich fibrin with connective tissue graft for the treatment of deep gingival recession defects: A controlled randomized clinical trial"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4252-174X","authenticated-orcid":false,"given":"Onur","family":"Ucak Turer","sequence":"first","affiliation":[{"name":"Department of Periodontology Cukurova University Adana 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