{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T20:36:31Z","timestamp":1768595791247,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:00:00Z","timestamp":1603843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005366","name":"Universitetet i Oslo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005366","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate clinical performance and side effects of two commercially available 0.2% chlorhexidine mouthwashes after periodontal surgery, one with (test) and one without (control) an anti\u2010discoloration system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This single\u2010centre, crossover clinical trial included 38 patients undergoing two sessions of periodontal flap surgery. The participants used two different 0.2% chlorhexidine products, one with and one without an anti\u2010discoloration system, in the 14\u2010day post\u2010operative periods. Plaque, gingival inflammation, tooth staining, side effects and patient preference were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The control mouthwash (without an anti\u2010discolouring system) produced significantly lower plaque (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.02) and gingival index (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.01) compared to the test mouthwash. The test mouthwash produced significantly less staining in the gingival (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.002) and approximal areas (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.0004), but no difference was detected in the buccal area of the teeth. The patients did not show preference for any of the mouthwashes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Chlorhexidine mouthwash without an anti\u2010discoloration system resulted in significantly lowered plaque and gingival index compared to chlorhexidine mouthwash with an anti\u2010discoloration following periodontal surgery. No difference in patient preference was found despite less side effects produced by the chlorhexidine mouthwash with the anti\u2010discoloration system.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13382","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T02:17:01Z","timestamp":1601950621000},"page":"1522-1527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of commercially available 0.2% chlorhexidine mouthwash with and without anti\u2010discoloration system: A blinded, crossover clinical trial"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5386-0176","authenticated-orcid":false,"given":"Erik Klepsland","family":"Mauland","sequence":"first","affiliation":[{"name":"Department of Periodontology Institute of Clinical Odontology Faculty of Dentistry University of Oslo Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans R.","family":"Preus","sequence":"additional","affiliation":[{"name":"Department of Periodontology Institute of Clinical Odontology Faculty of Dentistry University of Oslo Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Merete","family":"Aass","sequence":"additional","affiliation":[{"name":"Department of Periodontology Institute of Clinical Odontology Faculty of Dentistry University of Oslo Oslo Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2005.00117.x"},{"key":"e_1_2_8_3_1","first-page":"86","volume-title":"Practical statistics for medical research","author":"Altman D. 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