{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:01:00Z","timestamp":1791237660317,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2019MH006"],"award-info":[{"award-number":["ZR2019MH006"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the effects of glycine powder air\u2010polishing (GPAP) as an adjunct to full\u2010mouth scaling and root planing (SRP) on clinical, inflammatory and microbiological outcomes in patients with untreated periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Forty\u2010one patients were randomly assigned to the control group A (SRP) and test groups B1 (subgingival GPAP right after SRP) and B2 (subgingival GPAP right before SRP). Clinical examinations and sample collections (saliva, subgingival plaque, serum and gingival crevicular fluid) were performed at assessment visits and before therapies at clinical visits of baseline, 6\u2010week and 3\u2010month. C\u2010reactive protein, IL\u20106 and TNF\u2010\u03b1 were assessed in serum and gingival crevicular fluid, <jats:italic>Porphyromonas gingivalis<\/jats:italic>, <jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic> and <jats:italic>Fusobacterium nucleatum<\/jats:italic> were measured in saliva and subgingival plaque.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients in control and test groups did not significantly differ by age, sex and disease severity at baseline. Participants in control and intervention groups had similar improvements in clinical parameters (PD, BOP, PLI and BI). All groups had a similar percentage of sites showing PD reduction of \u22652\u00a0mm between baseline and follow\u2010up visits, with a few exceptions. Reduced C\u2010reactive protein, IL\u20106 and TNF\u2010\u03b1 in serum were found after treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Full\u2010mouth SRP with and without GPAP resulted in largely similar clinical, inflammatory and microbiological outcomes in the care of untreated periodontitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13400","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T08:23:11Z","timestamp":1605082991000},"page":"389-399","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Clinical, inflammatory and microbiological outcomes of full\u2010mouth scaling with adjunctive glycine powder air\u2010polishing: A randomized trial"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2388-1245","authenticated-orcid":false,"given":"Wenyi","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Periodontology School and Hospital of Stomatology Cheeloo College of Medicine Shandong University &amp; Shandong Key Laboratory of Oral Tissue Regeneration &amp; Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration Jinan China"},{"name":"Department of Periodontology Qingdao Stomatological Hospital Affiliated to Qingdao University Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontology Qingdao Stomatological Hospital Affiliated to Qingdao University Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cunchao","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Stomatology The Third People\u2019s Hospital of Qingdao Jimo District Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Jing","sequence":"additional","affiliation":[{"name":"Department of Periodontology Qingdao Stomatological Hospital Affiliated to Qingdao University Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nengliang (Aaron)","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Health Care Management Cheeloo College of Medicine Shandong University Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinfeng","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Periodontology School and Hospital of Stomatology Cheeloo College of Medicine Shandong University &amp; Shandong Key Laboratory of Oral Tissue Regeneration &amp; Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration Jinan 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