{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:45:54Z","timestamp":1790815554986,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T00:00:00Z","timestamp":1646697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess and compare the efficacy and safety of autogenous tooth roots (TRs) and autogenous bone blocks (ABs) for combined vertical and horizontal alveolar ridge augmentation and two\u2010stage implant placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A total of 28 patients in need of implant therapy and vertical ridge augmentation were allocated to parallel groups receiving either healthy autogenous tooth roots (e.g., retained wisdom teeth) (<jats:italic>n<\/jats:italic>\u00a0=\u00a014,<jats:italic>n<\/jats:italic>\u00a0=\u00a015 defects) or cortical autogenous bone blocks harvested from the retromolar area (<jats:italic>n<\/jats:italic>\u00a0=\u00a014,<jats:italic>n<\/jats:italic>\u00a0=\u00a017 defects). After 26\u2009weeks of submerged healing, the clinical reduction in ridge height (RH) deficiency was defined as the primary outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both surgical procedures were associated with a similar mean reduction in RH deficiency values, amounting to 4.48\u2009\u00b1\u20092.42\u2009mm (median: 4.25; 95% CI: 3.08\u20135.88) in the TR group and 4.46\u2009\u00b1\u20093.31\u2009mm (median: 3.00; 95% CI: 2.54\u20136.38) in the AB group (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.60, Mann\u2013Whitney<jats:italic>U<\/jats:italic>\u2010test). In all patients investigated, the reduction in RH deficiency values allowed for an adequate implant placement at the respective sites. The frequency of complications (e.g., soft tissue dehiscences) was low (TR:<jats:italic>n<\/jats:italic>\u00a0=\u00a04; AB:<jats:italic>n<\/jats:italic>\u00a0=\u00a00).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Up to staged\u2010implant placement, both TR and AB grafts appeared to be associated with comparable efficacy and safety for combined vertical and horizontal alveolar ridge augmentation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13609","type":"journal-article","created":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T11:50:15Z","timestamp":1646740215000},"page":"496-505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Efficacy of autogenous tooth roots for a combined vertical and horizontal alveolar ridge augmentation and staged implant placement. A prospective controlled clinical study"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5515-227X","authenticated-orcid":false,"given":"Frank","family":"Schwarz","sequence":"first","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Obreja","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Mayer","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ausra","family":"Ramanauskaite","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Sader","sequence":"additional","affiliation":[{"name":"Department for Oral, Cranio\u2010Maxillofacial and Facial Plastic Surgery Medical Center of the Goethe University Frankfurt Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puria","family":"Parvini","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Implantology Goethe University, Carolinum Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2012.06.003"},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/jcpe.13121","article-title":"Regeneration of alveolar ridge defects. Consensus report of group 4 of the 15th European Workshop on Periodontology on Bone Regeneration","volume":"46","author":"Jepsen S.","year":"2019","journal-title":"Journal of Clinical Periodontology"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-89996-6"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-019-02960-7"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-019-02869-1"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12267"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01301.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.00998.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12481"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12579"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13161"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12977"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13090"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13061"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.13609","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jcpe.13609","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.13609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T14:58:28Z","timestamp":1700319508000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.13609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,8]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/jcpe.13609"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.13609","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,8]]},"assertion":[{"value":"2021-11-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}