{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:04:55Z","timestamp":1791309895522,"version":"4.3.1"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T00:00:00Z","timestamp":1651190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the efficacy of different techniques to seal the alveolus (flap advancement [FA], open healing with barrier [OHB], and open healing without barrier [OHNB]) during alveolar ridge preservation (ARP) in terms of horizontal ridge width resorption.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Randomized trials of at least 2\u2009months duration comparing at least two techniques to seal the alveolus against each other or against spontaneous healing (SH) were eligible. Searches were conducted in MEDLINE via PubMed, EMBASE, Scopus, and Cochrane Central. Conventional meta\u2010analysis, meta\u2010regression, and network meta\u2010analysis (NMA) were conducted, with clinical and tomographic ridge width changes as outcomes. Predictive intervals (95% PI) were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010two studies were included, accounting for 52 study arms. Meta\u2010regression identified that the socket sealing technique and publication year explained the observed heterogeneity. NMA showed that FA and OHB led to significantly lower ridge resorption than SH, resulting in 1.18\u2009mm (95% PI 0.21\u20132.13) and 1.10\u2009mm (95% PI 0.49\u20131.69) wide alveolar ridges, respectively. No significant difference between OHNB and SH was found (0.46\u2009mm, 95% PI \u20130.70 to 1.64). The treatment with the largest probability for ARP was FA (52.7%), followed by OHB (39.1%) and OHNB (8.2%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>FA and OHB are efficacious techniques to seal the alveolus during ARP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13628","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T07:16:24Z","timestamp":1650611784000},"page":"694-705","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Comparison of the efficacy of different techniques to seal the alveolus during alveolar ridge preservation: Meta\u2010regression and network meta\u2010analysis"],"prefix":"10.1111","volume":"49","author":[{"given":"Jo\u00e3o Roig","family":"Martins","sequence":"first","affiliation":[{"name":"Periodontology, Faculty of Dentistry Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tassiane Panta","family":"Wagner","sequence":"additional","affiliation":[{"name":"Periodontology, Faculty of Dentistry Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina","family":"Vallim","sequence":"additional","affiliation":[{"name":"Periodontology, Faculty of Dentistry Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willian","family":"Konflanz","sequence":"additional","affiliation":[{"name":"Periodontology, Faculty of Dentistry Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falk","family":"Schwendicke","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Centre for Dental Medicine, Department of Oral Diagnostics and Digital Health and Health Services Research Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2468-6655","authenticated-orcid":false,"given":"Roger Keller","family":"Celeste","sequence":"additional","affiliation":[{"name":"Preventive and Social Dentistry, Faculty of Dentistry Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0531-6234","authenticated-orcid":false,"given":"Alex Nogueira","family":"Haas","sequence":"additional","affiliation":[{"name":"Periodontology, Faculty of Dentistry Federal University of Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,29]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"902","article-title":"Clinical and histologic healing of human extraction sockets filled with calcium sulfate","volume":"24","author":"Aimetti M.","year":"2009","journal-title":"The International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_9_3_1","first-page":"CD010176","article-title":"Interventions for replacing missing teeth: Alveolar ridge preservation techniques for dental implant site development","volume":"2015","author":"Atieh M. 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