{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:11:25Z","timestamp":1787015485225,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T00:00:00Z","timestamp":1673913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"Abstract<\/jats:title>\n \n Aim<\/jats:title>\n (i) To evaluate the efficacy of active periodontal therapy supplemented by supportive periodontal care (SPC) in retaining dentition during a 30\u2010year follow\u2010up period in patients susceptible to periodontitis, and (ii) to assess the prognostic factors associated with tooth loss.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n One\u2010hundred and fifty\u2010four patients with periodontitis, retrospectively classified as stage I\u2013IV and grade B\u2013C periodontitis, treated between 1984 and 1986 in a private practice, were enrolled in this study. After periodontal assessment, patients received non\u2010surgical treatment followed by surgical periodontal therapy, orthodontic treatment, and tooth\u2010splinting, where appropriate. SPC consisted of a strict recall programme every 3\u20136\u00a0months over a 30\u2010year period. Recurrences were treated either with subgingival root planing or flap surgery. Dental and periodontal variables were measured at baseline (T0), end of active therapy (T1), and after 25 (T2) and 30 (T3) years. Generalized mixed models were analysed to assess the prognostic factors associated with and survival analyses for tooth loss.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Data on 154 patients (4083 teeth) were available at baseline (T0). Teeth considered unworthy of treatment were extracted during active therapy (160, 3.9%) and at re\u2010assessment (13, 0.3%; T1). After 25\u2009years of SPC, 140 teeth out of 3910 in 154 patients (3.6%) were lost (24 in 18 patients for periodontal reasons). Between 25 and 30\u2009years, 20 patients (482 teeth) dropped out, and 61 teeth (2%) were lost (15 in 14 patients for periodontal reasons). Overall, 201 teeth (5.1%) were lost (39 for periodontal reasons) in 30\u2009years of SPC. Generalized mixed models showed that stage III or stage IV periodontitis was associated with greater tooth loss during SPC compared to stage I or stage II (OR\u00a0=\u00a02.10;\n p<\/jats:italic>\n \u00a0=\u00a0.048). Generalized periodontitis showed a statistically significant OR\u00a0=\u00a03.24 (\n p<\/jats:italic>\n \u00a0=\u00a0.016) compared to the localized one. In SPC (T1\u2013T3), age (\n p<\/jats:italic>\n \u00a0=\u00a0.011), gender (male;\n p<\/jats:italic>\n \u00a0=\u00a0.038), molar teeth (\n p<\/jats:italic>\n \u00a0=\u00a0<\u2009.001), T0 and T1 pocket depth (\n p<\/jats:italic>\n \u00a0=\u00a0<\u2009.001), tooth mobility grades 2 (\n p<\/jats:italic>\n \u00a0=\u00a0.018) and 3 (\n p<\/jats:italic>\n \u00a0=\u00a0.050), T0 and T1 bone loss (\n p<\/jats:italic>\n \u00a0=\u00a0<\u2009.001), and presence of a root canal treatment (\n p<\/jats:italic>\n \u00a0=\u00a0<\u2009.001) and a crown (\n p<\/jats:italic>\n \u00a0=\u00a0.009) were statistically significantly associated with tooth loss.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n (i) Periodontal therapy and a stringent SPC are effective in maintaining most of the teeth in patients with moderate\/advanced periodontitis for 30\u2009years, and (ii) age, gender, molar teeth, pocket depth, bone loss, and the presence of a root canal treatment and a crown are prognostic factors associated with tooth loss.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jcpe.13770","type":"journal-article","created":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T00:50:09Z","timestamp":1673484609000},"page":"520-532","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Longevity of teeth in patients susceptible to periodontitis: Clinical outcomes and risk factors associated with tooth loss after active therapy and 30\u2009years of supportive periodontal care"],"prefix":"10.1111","volume":"50","author":[{"given":"Giancarlo","family":"Agudio","sequence":"first","affiliation":[{"name":"Private Practice Bergamo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9945-0666","authenticated-orcid":false,"given":"Jacopo","family":"Buti","sequence":"additional","affiliation":[{"name":"Unit of Periodontology UCL Eastman Dental Institute London 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