{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:16:04Z","timestamp":1790712964660,"version":"4.1.0"},"reference-count":61,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the association between lifestyle behaviours and clinical periodontal outcomes following Steps 1\/2 of periodontal therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 120 subjects with untreated Stage II\/III periodontitis participated in this study. At baseline, questionnaires were administered to assess the following lifestyle behaviours: adherence to Mediterranean diet (MD), physical activity (PA) and stress levels, sleep quality, smoking and alcohol use. Participants received Steps 1\/2 of periodontal therapy and were re\u2010evaluated after 3\u2009months. A composite outcome of the endpoint of therapy (i.e., no sites with probing pocket depth [PPD] \u22654\u2009mm with bleeding on probing, and no sites with PPD\u2009\u2265\u20096\u2009mm) was regarded as the primary outcome. Simple and multiple regression analyses were used to evaluate the association between lifestyle behaviours and clinical periodontal outcomes. Disease severity at baseline, body mass index, diabetes, household disposable income and plaque control were considered as confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Multiple regression analyses showed significantly lower odds of achieving the endpoint of therapy in subjects with poor sleep quality (odds ratio [OR]\u2009=\u20090.13; 95% confidence interval [CI]: 0.03\u20130.47; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01), smoking (OR\u2009=\u20090.18; 95% CI: 0.06\u20130.52; <jats:italic>p<\/jats:italic>\u2009&lt; .05) and alcohol use above the suggested intake (OR\u2009=\u20090.21; 95% CI: 0.07\u20130.63; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01). Subjects with a combination of \u2018unhealthy lifestyles\u2019 (low adherence to MD and low PA levels and high levels of stress and poor sleep quality) showed higher proportions of residual PPD\u22656\u2009mm (MD\u2009=\u20091.51; 95% CI: 0.23\u20132.80; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) and lower odds of achieving the endpoint of therapy (OR\u2009=\u20090.85; 95% CI: 0.33\u20130.99; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) at re\u2010evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Subjects with unhealthy lifestyle behaviours showed worse clinical outcomes 3\u2009months after Steps 1\/2 of periodontal therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13813","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T07:59:56Z","timestamp":1680595196000},"page":"1089-1100","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Healthy lifestyles are associated with a better response to periodontal therapy: A prospective cohort study"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1088-2046","authenticated-orcid":false,"given":"Crystal","family":"Marruganti","sequence":"first","affiliation":[{"name":"Unit of Periodontology, Endodontology and Restorative Dentistry, Department of Medical Biotechnologies University of Siena  Siena 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Dentistry, Department of Medical Biotechnologies University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Parrini","sequence":"additional","affiliation":[{"name":"Unit of Oral Surgery, Department of Medical Biotechnologies University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8780-7306","authenticated-orcid":false,"given":"Filippo","family":"Graziani","sequence":"additional","affiliation":[{"name":"Sub\u2010Unit of Periodontology, Halitosis and Periodontal Medicine University Hospital of Pisa  Pisa Italy"},{"name":"Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Grandini","sequence":"additional","affiliation":[{"name":"Unit of Periodontology, Endodontology and Restorative Dentistry, Department of Medical 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