{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:21:15Z","timestamp":1789924875276,"version":"4.0.1"},"reference-count":44,"publisher":"Wiley","issue":"S26","license":[{"start":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T00:00:00Z","timestamp":1687219200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This systematic review aimed to evaluate the efficacy of supportive care provision, frequency and protocol in patients treated for peri\u2010implantitis, as reported in prospective and retrospective studies of at least 3\u2010years duration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A systematic search of three electronic databases was undertaken up to 21 July 2022 and supplemented by hand\u2010search to identify studies that included participants treated for peri\u2010implantitis and followed for at least 3\u2009years. Owing to high heterogeneity, a meta\u2010analysis was not appropriate, and therefore, data and risk of bias were explored qualitatively. PRISMA guidelines for reporting were followed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The search identified 2596 studies. Of 270 records selected during screening, 255 were excluded through independent review and 15 studies (10 prospective and 5 retrospective, with at least 20 patients) were retained for qualitative assessments. Study designs, population characteristics, supportive care protocols and reported outcomes varied markedly. Thirteen of the 15 studies had low risk of bias. Supportive peri\u2010implant care (SPIC) following different surgical peri\u2010implantitis treatment protocols and with recall intervals varying between 2\u2009months and annually resulted in peri\u2010implant tissue stability (no disease recurrence or progression) ranging from 24.4% to 100% at patient level and from 28.3% to 100% at implant level. Sevenhundred and eighty\u2010five patients with 790 implants were included in this review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Provision of SPIC following peri\u2010implantitis therapy may prevent disease recurrence or progression. Insufficient evidence is available to identify (i) a specific supportive care protocol for secondary prevention of peri\u2010implantitis, (ii) the effect of adjunctive local antiseptic agents in the secondary prevention of peri\u2010implantitis and (iii) the impact of frequency of supportive care measures. Prospective, randomised, controlled studies designed to evaluate supportive care protocols are needed in future.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13822","type":"journal-article","created":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T01:03:44Z","timestamp":1687309424000},"page":"113-134","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Supportive care for the prevention of disease recurrence\/progression following peri\u2010implantitis treatment: A systematic review"],"prefix":"10.1111","volume":"50","author":[{"given":"Meike","family":"Stiesch","sequence":"first","affiliation":[{"name":"Clinic of Prosthetic Dentistry and Biomedical Materials Science Hanover Medical School  Hanover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8165-2358","authenticated-orcid":false,"given":"Jasmin","family":"Grischke","sequence":"additional","affiliation":[{"name":"Clinic of Prosthetic Dentistry and Biomedical Materials Science Hanover Medical School  Hanover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Schaefer","sequence":"additional","affiliation":[{"name":"Clinic of Prosthetic Dentistry and Biomedical Materials Science Hanover Medical School  Hanover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa J. A.","family":"Heitz\u2010Mayfield","sequence":"additional","affiliation":[{"name":"International Research Collaborative Oral Health and Equity, School of Anatomy and Biology The University of Western Australia  Crawley Western Australia Australia"},{"name":"Discipline of Periodontics, School of Dentistry, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,20]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008505-200009030-00010"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13138"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13638"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12813"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515601961"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13653"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01759.x"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01819.x"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12334"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12562"},{"key":"e_1_2_14_12_1","first-page":"S21","article-title":"Treatment of peri\u2010implantitis: What interventions are effective? A Cochrane systematic review","volume":"5","author":"Esposito M.","year":"2012","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.2571"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.3489"},{"issue":"1","key":"e_1_2_14_15_1","first-page":"11","article-title":"Successful management of peri\u2010implantitis with a regenerative approach: A consecutive series of 51 treated implants with 3\u2010 to 7.5\u2010year follow\u2010up","volume":"32","author":"Froum S. J.","year":"2012","journal-title":"The International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13432"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-021-01529-9"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2011.02276.x"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2014suppl.g5.3"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12910"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-022-04493-y"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12661"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12369"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-020-03422-1"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13129"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.4691"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.11.1498"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13369"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.5051\/jpis.2103020151"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01245.x"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13256"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-4-200908180-00135"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1998.tb00124.x"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01742.x"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12227"},{"key":"e_1_2_14_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13628"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13287"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13818"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13028"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2009.01886.x"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01729.x"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01102.x"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12308"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13290"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12418"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.13822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T02:08:35Z","timestamp":1715911715000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.13822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":44,"journal-issue":{"issue":"S26","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1111\/jcpe.13822"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.13822","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"2022-10-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}