{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:21:42Z","timestamp":1783012902290,"version":"3.54.6"},"reference-count":54,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T00:00:00Z","timestamp":1697241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009748","name":"Ernhold Lundstr\u00f6ms stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009748","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["273838"],"award-info":[{"award-number":["273838"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the association between periodontitis and lung function in the Malm\u00f6 Offspring Dental Study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In all 1001 individuals (49.9% female, mean age: 44.6) from Malm\u00f6 Offspring Dental Study were included. Periodontitis was assessed by a full\u2010mouth examination protocol including bleeding on probing and classified according to the American Academy of Periodontology\/Center for Disease Control definitions. Forced expiratory volume in 1\u2009s (FEV<jats:sub>1<\/jats:sub>) and forced vital capacity (FVC) were expressed as absolute values and %predicted according to Global Lung Function Initiative reference values. FEV<jats:sub>1<\/jats:sub>, FVC and FEV<jats:sub>1<\/jats:sub>\/FVC were analysed in relation to periodontal status using linear regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Severe periodontitis was found in 7% of the population. Adjusted regression models showed significant associations between lung function and severe periodontitis with 2.1 unit lower FEV<jats:sub>1<\/jats:sub>\/FVC ratio (95% CI: \u22123.91, \u20130.23) and odds ratio (adjusted) of 2.56 (95% CI: 1.40, 4.75, <jats:italic>p<\/jats:italic>\u2009=\u2009.003) for airflow obstruction (FEV<jats:sub>1<\/jats:sub>\/FVC less than the lower limit of normal) if having severe periodontitis. Lower values of %predicted FEV<jats:sub>1<\/jats:sub> and %predicted FVC, but not FEV<jats:sub>1<\/jats:sub>\/FVC, were found in individuals with &gt;25% bleeding on probing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Severe periodontitis was associated with lower FEV<jats:sub>1<\/jats:sub>\/FVC ratio and airflow obstruction in the present cohort. More large\u2010scale prospective studies and intervention studies are required for a comprehensive evaluation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13886","type":"journal-article","created":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T09:10:01Z","timestamp":1697274601000},"page":"86-96","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Periodontitis is associated with airflow obstruction in the Malm\u00f6 Offspring Dental Study"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0352-5510","authenticated-orcid":false,"given":"Anders","family":"R\u00f8sland","sequence":"first","affiliation":[{"name":"Department of Clinical Dentistry, Section of Periodontics University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5319-525X","authenticated-orcid":false,"given":"Randi J.","family":"Bertelsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen  Bergen Norway"},{"name":"Oral Health Centre of Expertise in Western Norway  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8592-7467","authenticated-orcid":false,"given":"Dagmar F.","family":"Bun\u00e6s","sequence":"additional","affiliation":[{"name":"Department of Clinical Dentistry, Section of Periodontics University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4012-5492","authenticated-orcid":false,"given":"Christine","family":"Drengenes","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar","family":"Engstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund University  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2100-2446","authenticated-orcid":false,"given":"Bj\u00f8rn","family":"Klinge","sequence":"additional","affiliation":[{"name":"Faculty of Odontology Malm\u00f6 University  Malm\u00f6 Sweden"},{"name":"Department of Dental Medicine Karolinska Institutet  Solna Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4374-9276","authenticated-orcid":false,"given":"Stein\u2010Atle","family":"Lie","sequence":"additional","affiliation":[{"name":"Department of Clinical Dentistry, Section of Periodontics University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5652-8459","authenticated-orcid":false,"given":"Peter M.","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund University  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8298-539X","authenticated-orcid":false,"given":"Daniel","family":"J\u00f6nsson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Lund University  Malm\u00f6 Sweden"},{"name":"Faculty of Odontology Malm\u00f6 University  Malm\u00f6 Sweden"},{"name":"Public Dental Service of Sk\u00e5ne  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4098-7765","authenticated-orcid":false,"given":"Andrei","family":"Malinovschi","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Clinical Physiology Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,14]]},"reference":[{"issue":"4","key":"e_1_2_11_2_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J.","year":"1975","journal-title":"International Dental Journal"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-S002"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-021-01429-2"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-021-04000-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1993.tb00647.x"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-020-00695-4"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2018.1396876"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.21-0399"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2009.01144.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.140520"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/ejb.ejb_11_18"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00009811"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0147518"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3785"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12430"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01951-2018"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00109112"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2021.10.003"},{"key":"e_1_2_11_20_1","unstructured":"Journal of Internal Medicine Periodontal disease is associated with carotid plaque area: The malm\u00f6 offspring dental study (MODS)"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/idj.12535"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00063198-199903000-00005"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034514552491"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.120399"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb00852.x"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina55090581"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13303"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13767"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0095"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.4.1067"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13569"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13602"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060264"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0721"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191410"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67728-8"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080312"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12344"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00040708"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-017-0394-6"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2006.03.027"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003735"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01499-2021"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S327036"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60692-4"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyl049"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0576"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-241"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13076"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13287"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080537"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0046508"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12247"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S266612"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.13886","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,6]],"date-time":"2024-01-06T06:30:02Z","timestamp":1704522602000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.13886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,14]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/jcpe.13886"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.13886","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,14]]},"assertion":[{"value":"2023-01-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}