{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T23:15:20Z","timestamp":1783466120680,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100023551","name":"Cystic Fibrosis Ireland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023551","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010414","name":"Health Research Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010414","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009904","name":"College of International Security Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009904","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the prevalence of gingivitis and periodontitis, and the oral hygiene status of adults with cystic fibrosis (CF) in the Republic of Ireland.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A case\u2013control study in the form of a clinical examination of 92 adults with a diagnosis of CF was carried out in the adult CF unit in Cork University Hospital. A 40\u2010item questionnaire was used to capture socio\u2010demographic variables and medical and dental information. Two calibrated examiners carried out a periodontal assessment on participants, using the WHO\u2010recommended CPI\u2010modified index, and oral hygiene status was measured using the Greene\u2013Vermillion index. The results were compared with a population\u2010based control group of similar socio\u2010demographic profile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Oral hygiene levels (plaque and calculus) were significantly worse in people with CF, with a median plaque index of 0.83 (interquartile range [IQR] 0.333\u20131.542) in the CF group compared with 0.5 (IQR 0.167\u20130.667) in the non\u2010CF group. Calculus index in the CF group was 0.33 (IQR 0.17\u20130.83) compared with 0.33 (IQR 0.125\u20130.33) in the non\u2010CF group. However, periodontal disease levels were significantly lower in the CF group. Gingivitis (bleeding on probing\u2009\u2265\u200910% sites) was seen in 67.4% of the CF group, compared with 83.7% of the non\u2010CF group, OR 0.365 (95% confidence interval [CI] 0.181\u20130.736), relative risk (RR) 0.779 (95% CI 0.655\u20130.928). Mild periodontitis (periodontal probing depth\u2009[PPD] &lt;\u20095\u2009mm) was seen in 15.2% of the CF group, compared with 31.5% of the non\u2010CF group, OR 0.390 (CI 0.190\u20130.800), RR 0.483 (95% CI 0.273\u20130.852). Severe periodontitis (PPD\u2009\u2265\u20096\u2009mm) was seen in 0% of the CF group, compared with 9.8% of the non\u2010CF group. There was a tendency, albeit non\u2010significant, towards reduced periodontitis in PWCF who regularly took antibiotics, particularly azithromycin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this study, adults with CF had poor oral hygiene practices, with high levels of plaque and calculus. Despite this finding, adults with CF had lower levels of clinical gingivitis and periodontitis than seen in a non\u2010CF control group. Further study is required to examine the causes of this phenomenon.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13944","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T01:44:40Z","timestamp":1705542280000},"page":"571-582","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Periodontal disease prevalence and oral hygiene status of adults with cystic fibrosis: A case\u2013control study"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9421-5392","authenticated-orcid":false,"given":"Niamh","family":"Coffey","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry University College Cork  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"O'Leary","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry University College Cork  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Burke","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry University College Cork  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Kirwan","sequence":"additional","affiliation":[{"name":"Cystic Fibrosis Registry of Ireland University College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"O'Regan","sequence":"additional","affiliation":[{"name":"Cystic Fibrosis Registry of Ireland University College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry","family":"Plant","sequence":"additional","affiliation":[{"name":"Adult Cystic Fibrosis Unit Cork University Hospital  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry University College Cork  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Hayes","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Dublin Dental University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.22756"},{"issue":"4","key":"e_1_2_13_3_1","first-page":"181","article-title":"Oral hygiene habits and oral health in cystic fibrosis","volume":"3","author":"Aps J. K.","year":"2002","journal-title":"European Journal of Paediatric Dentistry"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2002.121280"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2012.06.011"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1977.0542"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.00368-15"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12935"},{"key":"e_1_2_13_9_1","volume-title":"CF: Treatment and therapies","author":"CFF","year":"2020"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0719"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2018.05.004"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12773"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2020.103509"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.012717"},{"key":"e_1_2_13_15_1","unstructured":"Cystic Fibrosis Registry of Ireland. (2023).2021 annual report CF Registry of Ireland.https:\/\/pub.flowpaper.com\/docs\/https:\/\/cfri.ie\/wp-content\/uploads\/2023\/01\/CFRI_2021_Annual_Report.pdf"},{"issue":"1","key":"e_1_2_13_16_1","first-page":"100","article-title":"Assessment of dental status and oral hygiene in the study population of cystic fibrosis patients in the Podlasie province","volume":"51","author":"Dabrowska E.","year":"2006","journal-title":"Advances in Medical Sciences"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.1737"},{"issue":"2","key":"e_1_2_13_18_1","first-page":"65","article-title":"Dental and periodontal health status in children affected by cystic fibrosis in a southern Italian region","volume":"10","author":"Ferrazzano G. F.","year":"2009","journal-title":"European Journal of Paediatric Dentistry"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2013.130369"},{"issue":"2","key":"e_1_2_13_20_1","first-page":"113","volume":"6","author":"Kinirons M. J.","year":"1989","journal-title":"Community Dental Health"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0089-x"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00068-09"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1965.36.3.177"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25733"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.88.8.702"},{"key":"e_1_2_13_26_1","unstructured":"NHS. (2020).Treating cystic fibrosis. Retrieved February 27 2020 fromhttps:\/\/www.nhsinform.scot\/illnesses-and-conditions\/lungs-and-airways\/cystic-fibrosis#treating-cystic-fibrosis"},{"key":"e_1_2_13_27_1","volume-title":"European Cystic Fibrosis Society Patient Registry annual report 2020","author":"Orenti A.","year":"2022"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.33073\/pjm-2019-040"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-014-0112-5"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-008-0693-2"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-020-0661-5"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.1.50"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1996.67.10s.1114"},{"key":"e_1_2_13_34_1","unstructured":"Trust C. F.(2022).UK cystic fibrosis registry annual data report 2021.https:\/\/www.cysticfibrosis.org.uk\/the-work-we-do\/uk-cf-registry\/reporting-and-resources"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_2_13_36_1","volume-title":"Oral health surveys: Basic methods","author":"WHO","year":"2013"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13819"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep30926"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.13944","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.13944","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T07:54:37Z","timestamp":1713340477000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.13944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,17]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1111\/jcpe.13944"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.13944","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,17]]},"assertion":[{"value":"2023-05-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}