{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:21:37Z","timestamp":1787224897309,"version":"build-2736575974"},"reference-count":47,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T00:00:00Z","timestamp":1710374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007619","name":"Osteology Foundation","doi-asserted-by":"publisher","award":["18\u2010040"],"award-info":[{"award-number":["18\u2010040"]}],"id":[{"id":"10.13039\/501100007619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the effects of implant timing and type of soft\u2010tissue grafting on histological and histomorphometric outcomes in a preclinical model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Four implant placement protocols were randomly applied at the mesial root sites of the third and fourth mandibular premolars in 10 mongrel dogs: immediate placement (group IP), early placement (group EP), delayed placement with\/without alveolar ridge preservation (groups ARP and DP, respectively). A connective\u2010tissue graft (CTG) or porcine\u2010derived volume\u2010stable collagen matrix (VCMX) was applied to enhance the ridge profile (simultaneously with implant placement in group IP and staged for others), resulting in five sites for each combination. All dogs were sacrificed 3\u2009months after soft\u2010tissue grafting. Histological and histomorphometric analyses were performed, and the data were analysed descriptively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CTG and VCMX were difficult to differentiate from the augmented area. The median total tissue thickness on the buccal aspect of the implant was largest in group IP\/CTG (between 2.78 and 3.87\u2009mm). The soft\u2010tissue thickness was generally favourable with CTG at all implant placement timings. Within the DP groups, CTG yielded statistically significantly larger total and soft\u2010tissue thickness than VCMX (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Among the groups with VCMX, group EP\/VCMX showed the largest soft\u2010tissue thickness at apical levels to the implant shoulder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CTG generally led to greater tissue thickness than VCMX.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13974","type":"journal-article","created":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T10:58:16Z","timestamp":1710413896000},"page":"840-851","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effects of implant placement timing\u00a0and type of soft\u2010tissue grafting on histological and histomorphometric outcomes in a preclinical canine model"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7695-1708","authenticated-orcid":false,"given":"Hyun\u2010Chang","family":"Lim","sequence":"first","affiliation":[{"name":"Department of Periodontology, Kyung Hee University, College of Dentistry, Periodontal\u2010Implant Clinical Research Institute Kyung Hee University Medical Center  Seoul Republic of Korea"},{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang\u2010Seok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Kyung Hee University, College of Dentistry, Periodontal\u2010Implant Clinical Research Institute Kyung Hee University Medical Center  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6980-7556","authenticated-orcid":false,"given":"Seung\u2010Yun","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Kyung Hee University, College of Dentistry, Periodontal\u2010Implant Clinical Research Institute Kyung Hee University Medical Center  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2055-1320","authenticated-orcid":false,"given":"Ronald E.","family":"Jung","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6371-4172","authenticated-orcid":false,"given":"Ui\u2010Won","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration Yonsei University College of Dentistry  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1764-7447","authenticated-orcid":false,"given":"Daniel S.","family":"Thoma","sequence":"additional","affiliation":[{"name":"Clinic of Reconstructive Dentistry, Center of Dental Medicine University of Zurich  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