{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T20:53:13Z","timestamp":1788209593651,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the effectiveness of a flapless surgical approach in the treatment of peri\u2010implantitis and to explore the factors influencing its outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The present retrospective study evaluated patients with at least one implant diagnosed with peri\u2010implantitis and treated with a flapless surgical access, with or without systemic antimicrobials, curettage and, when needed, prostheses modification. Clinical and radiographic parameters were assessed at baseline and at 3\u2009months and at least 12\u2009months. The primary outcome was disease resolution (\u22641 bleeding sites, probing depth [PD] \u22645\u2009mm, no bone loss &gt;0.5\u2009mm). Multilevel regression analyses were used to identify predictors influencing the probability of attaining disease resolution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and seventeen patients with 338 implants were included. Disease resolution was attained in 54.4% of the 338 implants receiving flapless surgical access. At the end of the follow\u2010up period, 111 patients (94.9%) with 295 implants (87.3%) did not require any further treatment, with 81.4% of these implants presenting PD\u2009\u2264\u20095\u2009mm. History of periodontitis and PD at baseline were identified as negative predictors, while compliance with supportive peri\u2010implant care, a machined surface and the adjunctive use of systemic azithromycin or metronidazole were identified as positive predictive factors for disease resolution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A flapless surgical approach led to disease resolution in 54.4% of the implants with peri\u2010implantitis. Several risk\/protective predictors for disease resolution were identified.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.13993","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T08:59:55Z","timestamp":1714553995000},"page":"968-980","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Treatment of peri\u2010implantitis with a flapless surgical access combined with implant surface decontamination and adjunctive systemic antibiotics: A retrospective case series study"],"prefix":"10.1111","volume":"51","author":[{"given":"Ana","family":"Carrillo de Albornoz","sequence":"first","affiliation":[{"name":"Etiology and Therapy of Periodontal and Peri\u2010implant Diseases (ETEP) Research Group, Faculty of Dentistry University Complutense of Madrid  Madrid Spain"},{"name":"Section of Graduate Periodontology University Complutense  Madrid 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