{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T21:33:34Z","timestamp":1792445614383,"version":"4.5.0"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T00:00:00Z","timestamp":1716768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015652","name":"Barts Charity","doi-asserted-by":"publisher","award":["MGU0504"],"award-info":[{"award-number":["MGU0504"]}],"id":[{"id":"10.13039\/100015652","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This prospective cohort study investigated the association between periodontal diseases (PDs) and all\u2010cause and cause\u2010specific mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We utilized adult participants recruited from six National Health and Nutrition Examination Survey cycles (1999\u20132014) and linked mortality data from the National Death Index up to December 2019. Baseline clinical periodontal examinations were performed by trained and calibrated examiners. All\u2010cause and cause\u2010specific mortality was modelled through multivariable Cox proportional hazards and Fine\u2013Gray models to account for competing risks. All models were adjusted for demographic and lifestyle variables, clinical measurements and comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 15,030 participants were included, with a median length of follow\u2010up of 9\u2009years. Risk of all\u2010cause mortality was 22% greater in people with PD than the control group (adjusted hazard ratio [HR]: 1.22, 95% confidence interval [CI]: 1.12\u20131.31). Risks of mortality by cardiovascular diseases (CVD), respiratory disease and diabetes were highest in participants with severe PD (CVD\u2014sub\u2010distribution HR [SHR]: 1.38, 95% CI: 1.16\u20131.64; respiratory\u2014SHR: 1.62, 95% CI: 1.07\u20132.45; diabetes\u2014SHR: 1.68, 95% CI: 1.12\u20132.53).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Severe PD is associated with all\u2010cause and cause\u2010specific mortality among US adults after multivariable adjustment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.14002","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T02:25:27Z","timestamp":1716863127000},"page":"1157-1167","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["All\u2010cause and cause\u2010specific mortality in <scp>US<\/scp> adults with periodontal diseases: A prospective cohort study"],"prefix":"10.1111","volume":"51","author":[{"given":"Harriet","family":"Larvin","sequence":"first","affiliation":[{"name":"Wolfson Institute of Population Health Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2565-8525","authenticated-orcid":false,"given":"Paris J.","family":"Baptiste","sequence":"additional","affiliation":[{"name":"Wolfson Institute of Population Health Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1163-2751","authenticated-orcid":false,"given":"Chenyi","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Dentistry University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Muirhead","sequence":"additional","affiliation":[{"name":"Centre for Oral Clinical Research, Institute of Dentistry Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Donos","sequence":"additional","affiliation":[{"name":"Centre for Oral Clinical Research, Institute of Dentistry Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Pavitt","sequence":"additional","affiliation":[{"name":"School of Dentistry University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2770-1099","authenticated-orcid":false,"given":"Jing","family":"Kang","sequence":"additional","affiliation":[{"name":"Oral Biology, School of Dentistry University of Leeds  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6093-599X","authenticated-orcid":false,"given":"Jianhua","family":"Wu","sequence":"additional","affiliation":[{"name":"Wolfson Institute of Population Health Queen Mary University of London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.5051\/jpis.2100920046"},{"key":"e_1_2_11_3_1","volume-title":"National Center for Health Statistics (NCHS). 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