{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:57:01Z","timestamp":1785884221862,"version":"3.56.0"},"reference-count":45,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270188"],"award-info":[{"award-number":["32270188"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32070134"],"award-info":[{"award-number":["32070134"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aims to investigate the early alterations in microbiome construction and succession around dental implants in both periodontally healthy individuals and patients with a history of periodontitis during the first month after implant\u2013crown placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Ninety\u2010five subgingival plaque samples were collected from 10 periodontally compromised patients (PCP) and nine periodontally healthy patients (PHP) at four time points with a 1\u2010week interval and analysed using dynamic metagenomic analysis. The study compared the formation and temporal change in the peri\u2010implant microbiome in the PCP and PHP groups during the first month after the implant crown placement. A two\u2010year follow\u2010up examination was conducted to assess the clinical outcomes of early peri\u2010implant dysbiosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results showed that PCP groups exhibited distinctively dysbiotic features in their peri\u2010implant microbiome upon initial establishment, with an earlier and elevated emergence of periodontopathogens. This dysbiosis in the PCP group was associated with significantly higher modified sulcus bleeding index (mBI) scores compared with the PHP group. <jats:italic>Neisseria<\/jats:italic> was identified as a key driver of early peri\u2010implant dysbiosis in patients with a periodontitis history.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study established the first microbial link between periodontitis history and early peri\u2010implant dysbiosis, highlighting the importance of early prevention strategies against peri\u2010implant diseases in patients with a periodontitis history.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.14147","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T17:02:49Z","timestamp":1741712569000},"page":"1011-1023","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Periodontitis History Shapes the Early Peri\u2010Implant 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