{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T04:12:25Z","timestamp":1790914345169,"version":"4.1.0"},"reference-count":43,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013699","name":"Bundesministerium f\u00fcr Bildung, Wissenschaft und Forschung","doi-asserted-by":"publisher","award":["ZZ9603"],"award-info":[{"award-number":["ZZ9603"]}],"id":[{"id":"10.13039\/501100013699","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013699","name":"Bundesministerium f\u00fcr Bildung, Wissenschaft und Forschung","doi-asserted-by":"publisher","award":["01ZZ0103"],"award-info":[{"award-number":["01ZZ0103"]}],"id":[{"id":"10.13039\/501100013699","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013699","name":"Bundesministerium f\u00fcr Bildung, Wissenschaft und Forschung","doi-asserted-by":"publisher","award":["01ZZ0403"],"award-info":[{"award-number":["01ZZ0403"]}],"id":[{"id":"10.13039\/501100013699","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the association of alcohol consumption with periodontitis risk and change in periodontal parameters over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using data from 1285 participants of two population cohort studies embedded in the Study of Health in Pomerania, we associated baseline average alcohol consumption with incident periodontitis measured after a median follow\u2010up time of 5.0\u2009years, adjusting for confounding and selection bias using multivariable regression and multiple imputation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Baseline alcohol intake was prospectively associated with a higher risk of periodontitis (relative risk of 1.08 (95% confidence interval: 1.06, 1.10) and 1.23 (1.17, 1.28) for 30 and 60\u2009g per day (g\/day) versus 10\u2009g\/day), deeper periodontal pockets, higher clinical attachment levels (CAL) and a higher proportion of sites with probing depths and CAL \u2265\u20093\u2009mm and \u2265 4\u2009mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results support the hypothesis that higher alcohol intake modestly increases the risk of periodontitis. Sensitivity analysis suggested that unmeasured confounding and selection bias could explain the observed association.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jcpe.14154","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T19:15:06Z","timestamp":1741893306000},"page":"1024-1031","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Alcohol Consumption, Risk of Periodontitis and Change of Periodontal Parameters in a Population\u2010Based Cohort Study"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9391-6602","authenticated-orcid":false,"given":"Sebastian\u2010Edgar","family":"Baumeister","sequence":"first","affiliation":[{"name":"Institute of Health Services Research in Dentistry University of M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janka","family":"Sch\u00f6ssow","sequence":"additional","affiliation":[{"name":"Institute for Community Medicine University Medicine Greifswald  Greifswald Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4288-6300","authenticated-orcid":false,"given":"Gustavo G.","family":"Nascimento","sequence":"additional","affiliation":[{"name":"National Dental Research Institute Singapore, National Dental Centre Singapore Oral Health Academic Clinical Programme, Duke\u2010NUS Medical School  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"V\u00f6lzke","sequence":"additional","affiliation":[{"name":"Institute for Community Medicine University Medicine Greifswald  Greifswald Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Kocher","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Periodontology, and Endodontology University Medicine Greifswald  Greifswald Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birte","family":"Holtfreter","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Periodontology, and Endodontology University Medicine Greifswald  Greifswald Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13376"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2015.09.001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13544"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/2047487317738594"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201035337\u20108"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12685"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a112408"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.5686"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100528.2008.00435.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.110664"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)00847\u20109"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jphd.12213"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034521995428"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010023\u201002383\u20108"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwaa071"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kww122"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000001377"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhealeco.2004.09.011"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.6553"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/acer.15478"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.15692"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.13337"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100765.2006.00907.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2023.02.002"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agac023"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910308200704"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1922\/CDH_4569Pulikkotil10"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn093"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.19\u20100602"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/eos.12610"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41512\u2010020\u201000074\u20103"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000001380"},{"issue":"2","key":"e_1_2_9_34_1","first-page":"159","article-title":"Alcohol's Effect on Host Defense","volume":"37","author":"Szabo G.","year":"2015","journal-title":"Alcohol Research: Current Reviews"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2020.2588"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127\u2010016\u20101281\u20109"},{"key":"e_1_2_9_37_1","first-page":"263","volume-title":"Modern Epidemiology","author":"VanderWeele T. J.","year":"2021"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyac034"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2017.170231"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12556"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4067"},{"key":"e_1_2_9_42_1","volume-title":"Global Status Report on Alcohol and Health","author":"WHO","year":"2018"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.10274"},{"key":"e_1_2_9_44_1","volume-title":"Econometric Analysis of Cross Section and Panel Data","author":"Wooldridge J. M.","year":"2010"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.14154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:50:25Z","timestamp":1754527825000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.14154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,13]]},"references-count":43,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/jcpe.14154"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.14154","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,13]]},"assertion":[{"value":"2024-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}