{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T07:32:16Z","timestamp":1793345536396,"version":"4.5.0"},"reference-count":71,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T00:00:00Z","timestamp":1757808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T00:00:00Z","timestamp":1757808000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate the impact of ultra\u2010processed foods reduction advice (UPF\u2010RA) on gingivitis treatment and dietary patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Young adults with gingivitis were randomly assigned to two groups. At baseline, test group participants received UPF\u2010RA. At 8\u2009weeks, professional mechanical plaque removal (PMPR) was carried out, followed by UPF\u2010RA (test group only). Full\u2010mouth periodontal charting and dietary data, collected through the NOVA Food Frequency Questionnaire and the Medi\u2010Lite, were recorded at baseline and at 8 and 16\u2009weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty\u2010six patients (mean age: 23.3\u2009\u00b1\u20092.3\u2009years; 32 males and 34 females) were included. At 8\u2009weeks, a significant reduction in full\u2010mouth bleeding score (FMBS) was observed in the test group (18.9%\u2009\u00b1\u20098.6% to 14.6%\u2009\u00b1\u20099.0%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), with a concomitant decrease in UPF intake (912.7\u2009\u00b1\u2009511.3\u2009kcal to 446.9\u2009\u00b1\u2009264.6\u2009kcal;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). No significant changes in FMBS and UPF consumption were observed in the control group (19.8%\u2009\u00b1\u20099.0% to 19.1%\u2009\u00b1\u20098.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.93; 776.4\u2009\u00b1\u2009453.6\u2009kcal to 775.3\u2009\u00b1\u2009451.03,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.00, respectively). At 16\u2009weeks, gingivitis was resolved in 24% more cases in the test group. Logistic regression identified low UPF intake and UPF\u2010RA as significant predictors of FMBS reduction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Reduction in UPF consumption improved gingivitis treatment outcomes and participants' dietary quality. Patients with higher UPF consumption showed higher bleeding scores.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpe.70034","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T04:10:00Z","timestamp":1757909400000},"page":"12-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Ultra\u2010Processed Foods Reduction Enhances Clinical Outcomes and Dietary Profiles in Patients With Gingivitis: Results From a Randomised Controlled Trial"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1805-2899","authenticated-orcid":false,"given":"Nicola","family":"Discepoli","sequence":"first","affiliation":[{"name":"Unit of Periodontics, Department of Medical Biotechnologies University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8704-5813","authenticated-orcid":false,"given":"Isabella","family":"De Rubertis","sequence":"additional","affiliation":[{"name":"Unit of Periodontics, Department of Medical Biotechnologies University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Tavella","sequence":"additional","affiliation":[{"name":"Unit of Dietetics and Clinical Nutrition, Department of Medical Sciences, Santa Maria Alle Scotte Hospital University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Guazzelli","sequence":"additional","affiliation":[{"name":"Unit of Periodontics, Department of Medical Biotechnologies University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Styliani","family":"Konstantinidou","sequence":"additional","affiliation":[{"name":"Unit of Periodontics, Department of Medical Biotechnologies University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Paolini","sequence":"additional","affiliation":[{"name":"Unit of Dietetics and Clinical Nutrition, Department of Medical Sciences, Santa Maria Alle Scotte Hospital University of Siena  Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,14]]},"reference":[{"issue":"4","key":"e_1_2_11_2_1","first-page":"229","article-title":"Problems and Proposals for Recording Gingivitis and Plaque","volume":"25","author":"Ainamo J.","year":"1975","journal-title":"International Dental Journal"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.13961"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/IDH.12739"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.13576"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.21\u20100274"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqaa299"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/JDD.12448"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.ENFCLI.2018.03.002"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17\u20100719"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.IMMUNI.2019.09.020"},{"issue":"1","key":"e_1_2_11_12_1","first-page":"176","article-title":"Nutrition Education: Linking Research, Theory, and Practice","volume":"17","author":"Contento I. R.","year":"2008","journal-title":"Asia Pacific Journal of Clinical Nutrition"},{"issue":"3","key":"e_1_2_11_13_1","first-page":"239","article-title":"Validation of the Italian Version of the Oral Health Impact Profile\u201014 (IOHIP\u201014)","volume":"4","author":"Corridore D.","year":"2014","journal-title":"Annali di Stomatologia"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/EJE.12822"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980020001524"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12664"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU14102073"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/09637486.2021.1880552"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100757.2011.00413.X"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13587"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.12.1440"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6FO00107F"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7FO01423F"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/HEALTHCARE10060984"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.16065"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JACC.2006.03.052"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph191811360"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0148"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509337700"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980017001367"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/ADVANCES\/NMAB086"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13679\u2010024\u201000569\u2010w"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JAD.2023.04.124"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb00424.x"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41430\u2010017\u20100039\u20100"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.114.089656"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU13041194"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JDENT.2025.105644"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU13082778\/S1"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.21-0643"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.26082\u20100"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472\u20106831\u20106\u2010S1\u2010S14"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102288\u20107\u201030"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980018003762"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980017000234"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.3148\/75.1.2014.15"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0095"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12341"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1972.43.1.38"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114520002688"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.24\u20100208"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13690"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980021002767"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13290"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0117959"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12571\u2010017\u20100678\u2010y"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100528.1997.tb00941.x"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1344"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1080\/09637486.2017.1287884"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15153344"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.IMMUNI.2014.05.014"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.12382"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU15061546"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12939"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/OBR.12860"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13817"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/SJ.BDJ.2012.1088"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13094"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.13831"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.3390\/NU15061538\/S1"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15204319"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13979"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.70034","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jcpe.70034","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.70034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T06:56:21Z","timestamp":1793343381000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.70034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,14]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/jcpe.70034"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.70034","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,14]]},"assertion":[{"value":"2025-05-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}