{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:47:57Z","timestamp":1782301677919,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim<\/jats:title>\n                    <jats:p>Effective oral hygiene using different mechanical means is mainly dependent on the patient. Mouthwashes containing antimicrobial agents have been developed to be used as an adjunct to mechanical supragingival plaque control. The aim of this umbrella review is to evaluate and compare the long\u2010term efficacy of commonly used, commercially available daily mouthwashes in plaque control and gingival inflammation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The current umbrella review was conducted in accordance with the\n                      <jats:italic>Cochrane Handbook for Systematic Reviews of Interventions<\/jats:italic>\n                      using the PICOS format. The search was conducted in four databases: PubMed, Scopus, Cochrane and Web of Science. Nine systematic reviews\/meta\u2010analyses (SRs\/MAs) on the long\u2010term efficacy of commercially available mouthwashes (low\u2010concentration chlorhexidine [CHX], cetylpyridinium chloride [CPC], mouthwashes with essential oils [EOs], fluoride and oxygen\u2010releasing mouthwashes) were included.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The results revealed that in all SRs\/MAs, the prolonged daily use of mouthwashes helped in reducing plaque and gingival inflammation indices but not always with statistical significance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Results of the present study indicate that the long\u2010term use of mouthwashes containing EOs seems to give the best results in both reducing plaque levels and improving gingivitis indices among all tested formulations.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      PROSPERO Registration Number CRD 42024618552\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpe.70061","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T23:49:08Z","timestamp":1763682548000},"page":"407-423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Adjunctive Use of Commercial Daily Mouthwashes on Periodontal Health: An Umbrella Review"],"prefix":"10.1111","volume":"53","author":[{"given":"Panagiotis A.","family":"Koromantzos","sequence":"first","affiliation":[{"name":"Department of Periodontology, School of Dentistry National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiorgos A.","family":"Bobetsis","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dentistry National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrysoula","family":"Giota","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dentistry National and Kapodistrian University of Athens  Athens Greece"},{"name":"Department of Preventive and Community Dentistry, School of Dentistry National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotiria","family":"Gizani","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, School of Dentistry National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danae Anastasia","family":"Apatzidou","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, Periodontology &amp; Implant Biology, Dental School Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Rahiotis","sequence":"additional","affiliation":[{"name":"Department of Operative Dentistry, School of Dentistry National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotirios","family":"Kalfas","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, Periodontology &amp; Implant Biology, Dental School Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyriaki","family":"Seremidi","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, School of Dentistry National and Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Papadimitriou","sequence":"additional","affiliation":[{"name":"Department of Preventive Dentistry, Periodontology &amp; 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