{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:31:31Z","timestamp":1791912691852,"version":"4.3.4"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the associations between peri\u2010implant phenotype characteristics and long\u2010term outcomes of soft tissue\u2013level implants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty\u2010five tissue\u2010level implants from a previous controlled clinical trial\u00a0were evaluated at 1\u2010 and 5\u2010year follow\u2010ups after crown delivery. Data included ultrasonographic scans (mucosal thickness and supracrestal tissue height), standardised 2D radiographs, cone beam computed tomography, clinical outcomes (mucosal recession, probing pocket depth, bleeding on probing), patient\u2010reported outcomes and peri\u2010implant health status. Standard logistic and linear regression models were used to analyse associations of implant\u2010 and patient\u2010related factors with outcomes, including peri\u2010implant disease status, mucosal recession and marginal bone level (MBL) changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Five\u2010year implant survival was 100%, with peri\u2010implant mucositis diagnosed in 36% of the implants. Mean MBL changes from the first to the fifth year was 0.29\u2009\u00b1\u20090.29\u2009mm. Baseline (pre\u2010surgical) buccal soft\u2010tissue thickness &lt;\u20091.5\u2009mm (OR: 5.20,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007) and increased plaque scores (OR: 30.11,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) were associated with peri\u2010implant mucositis, whereas buccal bone thickness \u2265\u20091.5\u2009mm (OR: 0.48,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.039), mucosal thickness around implant (OR: 0.20,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001) and supracrestal tissue height (OR: 0.50,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) emerged as protective factors. Mucosal recession was significantly associated with baseline buccal soft\u2010tissue thickness &lt;\u20091.5\u2009mm (estimate\u2009=\u20090.27,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03) and keratinised mucosa width of &lt;\u20092\u2009mm (estimate\u2009=\u20090.39,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021). Clinical thresholds associated with long\u2010term peri\u2010implant health were defined as follows: supracrestal tissue height \u2265\u20092.8\u2009mm, restorative emergence angle \u2264\u200935.5\u00b0, mucosal thickness 1.8\u2009mm and buccal bone thickness 1.5\u2009mm. Patients reported a high overall satisfaction (visual analogue scale: 88.2%). Colour Doppler ultrasonography showed a strong correlation between tissue perfusion and peri\u2010implant disease (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.93,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Within the limitations of this study, tissue\u2010level implants showed excellent survival rates and patient satisfaction at 5\u2009years. Several peri\u2010implant parameters\u2014such as supracrestal tissue height \u2265\u20092.8\u2009mm, restorative emergence angle \u2264\u200935.5\u00b0 and buccal bone thickness \u2265\u20091.5\u2009mm\u2014were associated with favourable outcomes. These exploratory thresholds may be considered hypothesis\u2010generating and could help guide future research and clinical monitoring, although validation in larger cohorts is essential.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.clinicaltrials.gov\/study\/NCT02925078\">www.clinicaltrials.gov\/study\/NCT02925078<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpe.70062","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:39:29Z","timestamp":1765600769000},"page":"394-406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Impact of Peri\u2010Implant Phenotype on Implant Therapy Outcomes: A 5\u2010Year Cohort Analysis on Soft Tissue\u2014Level Implants"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6581-2104","authenticated-orcid":false,"given":"Hamoun","family":"Sabri","sequence":"first","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"},{"name":"Center for Clinical Research and Evidence Synthesis in Oral Tissue Regeneration (CRITERION)  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8362-3208","authenticated-orcid":false,"given":"Parham","family":"Hazrati","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4864-3964","authenticated-orcid":false,"given":"Lorenzo","family":"Tavelli","sequence":"additional","affiliation":[{"name":"Center for Clinical Research and Evidence Synthesis in Oral Tissue Regeneration (CRITERION)  Ann Arbor Michigan USA"},{"name":"Division of Periodontology, Department of Oral Medicine, Infection, and Immunity Harvard School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Garaicoa\u2010Pazmino","sequence":"additional","affiliation":[{"name":"Department of Periodontics University of Iowa College of Dentistry and Dental Clinics  Iowa City Iowa USA"},{"name":"School of Dentistry, Universidad de Especialidades Espiritu Santo  Samborondon 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