{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T15:37:39Z","timestamp":1785253059262,"version":"3.55.0"},"reference-count":58,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To describe the efficacy of steps I\u2013II\u2013III of periodontal therapy performed in a specialist university setting following EFP S3 treatment guideline and to assess factors associated with the achievement of endpoints of therapy (EoT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Records of 131 stage III\u2013IV periodontitis patients were collected retrospectively. Residual pockets (probing pocket depth [PPD] 5\u2009mm with bleeding on probing [BoP] or PPD\u2009\u2265\u20096\u2009mm) after steps I\u2013II (T1) received repeated subgingival instrumentation (RSI) or surgery and were re\u2010evaluated after 1\u2009year (T2). EoT (no PPD\u2009\u2265\u20095\u2009mm BoP+ and no PPD\u2009\u2265\u20096\u2009mm) rate at T1 and T2 was computed, and predictors explored through multilevel analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>At T1, EoT was 67.8%, with step III yielding an additional 90.0% of EoT in PPD\u2009=\u20095\u2009mm BoP+ and 85.3% in PPD\u2009\u2265\u20096\u2009mm. Factors negatively associated with EoT were: posterior teeth, furcation involvement (degree II\u2013III), initial PPD, interproximal location and plaque. When considering only pockets\u2009\u2265\u20096\u2009mm, factors were PPD at T1, type of intervention (resective surgery over RSI) and plaque at T2. Overall, 55.7% of patients reached EoT, 16.1% achieved \u2018stable periodontitis\u2019 (PPD\u2009\u2264\u20094\u2009mm, no PPD\u2009=\u20094\u2009mm BoP+, BoP\u2009&lt;\u200910%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Guideline\u2010based periodontal therapy achieved EoT targets in 93.3% of sites and 50% of patients with Stage III\u2013IV periodontitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpe.70087","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T02:57:12Z","timestamp":1768877832000},"page":"562-571","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Outcomes of Active Periodontal Therapy in a Specialist University Setting Following\n                    <scp>EFP S3<\/scp>\n                    Treatment Guideline in Stage III\u2013IV Periodontitis Patients"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0657-0787","authenticated-orcid":false,"given":"Mario","family":"Aimetti","sequence":"first","affiliation":[{"name":"Department of Surgical Sciences C.I.R. Dental School, University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5172-299X","authenticated-orcid":false,"given":"Federica","family":"Romano","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences C.I.R. Dental School, University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Costanzo","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences C.I.R. Dental School, University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"De Caroli","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences C.I.R. Dental School, University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Di Venanzio","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences C.I.R. Dental School, University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia Maria","family":"Mariani","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences C.I.R. Dental School, University of Turin  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9395-4967","authenticated-orcid":false,"given":"Giacomo","family":"Baima","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences C.I.R. 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