{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:03:53Z","timestamp":1789344233611,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T00:00:00Z","timestamp":1789257600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To quantify the incidence and develop predictive models for postoperative sequelae and complications (POSC) and the need for additional grafting after alveolar ridge augmentation with simultaneous implant placement (SARA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This longitudinal retrospective cohort included adults with ridge deficiencies who underwent SARA with implant placement from 2019 to 2024 at the University of Michigan Graduate Periodontics Clinic. One site per patient was analysed. Complications were classified according to the severity of consequences and need for further intervention. Univariable and multivariable logistic regression models were performed with stepwise refinement. Firth penalized logistic regression was used when sparse data\/separation were present. Model discrimination (area under the curve, AUC) and calibration (Hosmer\u2013Lemeshow, HL) were assessed; ROC\u2010derived thresholds were used to report operating characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Three\u2010hundred and ninety\u2010one patients were included. Systemic comorbidities were documented in 48.6%. Postoperative sequelae occurred in 31.5% of patients, and complications occurred in 25.8%. Membrane exposure was associated with vertical\/combined defects (adjusted odds ratio [aOR] 2.52; 95% CI: 1.50\u20134.23). Microsurgical technique was associated with lower odds of incision\u2010line dehiscence (aOR 0.76; 95% CI: 0.57\u20131.00;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.049). Prolonged swelling was\u00a0associated with flap extension (aOR 1.21 per tooth site; 95% CI: 1.04\u20131.39). Additional grafting occurred in 6.14% and was associated with clinical attachment loss (CAL \u2265\u20095\u2009mm on adjacent tooth [OR 14.07; 3.79\u201352.18;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001]), current smoking (OR 5.11; 1.38\u201318.95;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.015) and long\u2010term systemic corticosteroid use (OR 1.61; 1.04\u20132.51;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.035) (AUC 0.744; HL\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.5103).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Postoperative sequelae were more frequent than true complications, and the need for additional grafting was uncommon. Complications were mainly associated with defect morphology and surgical technique rather than systemic comorbidities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpe.70196","type":"journal-article","created":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:44:38Z","timestamp":1789343078000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Postoperative Sequelae and Complications of Alveolar Ridge Augmentation With Simultaneous Implant Placement. A Retrospective Cohort\u2010Based Predictive Risk Modelling"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-7317","authenticated-orcid":false,"given":"Muhammad H. A.","family":"Saleh","sequence":"first","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5427-8220","authenticated-orcid":false,"given":"Hend","family":"Abulatifa","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3756-3580","authenticated-orcid":false,"given":"Francesco","family":"Fanelli","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7437-6279","authenticated-orcid":false,"given":"Abdusalam E.","family":"Alrmali","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"},{"name":"Department of Oral Medicine, Oral Pathology, Oral and Maxillofacial Surgery University of Tripoli School of Dentistry  Tripoli Libya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2095-5026","authenticated-orcid":false,"given":"Asmaa W.","family":"Issa","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-1799","authenticated-orcid":false,"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, School of Dentistry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5647-4414","authenticated-orcid":false,"given":"Giuseppe","family":"Troiano","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12185"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2005.01106.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.70005"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13911"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12518"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2008.01269.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.70079"},{"issue":"3","key":"e_1_2_10_10_1","first-page":"265","article-title":"Clinical Classification of Complications in Guided Bone Regeneration Procedures by Means of a Nonresorbable Membrane","volume":"31","author":"Fontana F.","year":"2011","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.7214"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.14440"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12470"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.70176"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.11162"},{"issue":"6","key":"e_1_2_10_16_1","first-page":"495","article-title":"Simultaneous and Staged Approaches for Guided Bone Regeneration","volume":"21","author":"Kohavi D.","year":"2000","journal-title":"Compendium of Continuing Education in Dentistry"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12509"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0b013e31818c4992"},{"issue":"1","key":"e_1_2_10_19_1","first-page":"11","article-title":"Bone Augmentation at Implant Dehiscences and Fenestrations. A Systematic Review of Randomised Controlled Trials","volume":"9","author":"Merli M.","year":"2016","journal-title":"European Journal of Oral Implantology"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2013.12.004"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100501.2011.02295.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.70146"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.70060"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.70066"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12413"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515594780"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12409"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13087"},{"issue":"2","key":"e_1_2_10_29_1","first-page":"166","article-title":"A Comparative Study of the Effectiveness of e\u2010PTFE Membranes With and Without Early Exposure During the Healing Period","volume":"14","author":"Simion M.","year":"1994","journal-title":"International Journal of Periodontics & Restorative Dentistry"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.70021"},{"issue":"4","key":"e_1_2_10_31_1","first-page":"744","article-title":"Conventional and Advanced Implant Treatment in the Type II Diabetic Patient: Surgical Protocol and Long\u2010Term Clinical Results","volume":"23","author":"Tawil G.","year":"2008","journal-title":"International Journal of Oral & Maxillofacial Implants"},{"key":"e_1_2_10_32_1","unstructured":"Technical Requirements For Pharmaceuticals.2025.\u201cGuideline For Good Clinical Practice E6(R3).\u201dhttps:\/\/database.ich.org\/sites\/default\/files\/ICH_E6%28R3%29_Step4_FinalGuideline_2025_0106.pdf?utm_source=chatgpt.com."},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13050"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13808"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13061"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.14129"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.5590"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12512"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12726"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600\u2010051x.1999.261007.x"}],"container-title":["Journal of Clinical Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.70196","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jcpe.70196","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpe.70196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:44:40Z","timestamp":1789343080000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jcpe.70196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,13]]},"references-count":39,"alternative-id":["10.1111\/jcpe.70196"],"URL":"https:\/\/doi.org\/10.1111\/jcpe.70196","archive":["Portico"],"relation":{},"ISSN":["0303-6979","1600-051X"],"issn-type":[{"value":"0303-6979","type":"print"},{"value":"1600-051X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,13]]},"assertion":[{"value":"2026-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"jcpe.70196"}}