{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T01:06:31Z","timestamp":1788915991084,"version":"build-2803163510"},"reference-count":55,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clinic Periodontology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate clinical feasibility of 3D\u2010printed, patient\u2010specific, polycaprolactone (PCL) resorbable scaffolds for staged alveolar ridge augmentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Ten patients requiring staged bone augmentation underwent digital planning to virtually reconstruct the defect to its original contour. Patient\u2010specific medical\u2010grade PCL scaffolds were then fabricated using 3D printing and sterilised using \u03b3 irradiation. Following surgical access of the defect site, the scaffolds were loaded with a composite graft of autogenous bone, deproteinised bovine bone mineral and injectable platelet\u2010rich fibrin, and covered with a resorbable collagen membrane. Clinical reviews were performed at 1, 3 and 8\u2009weeks. Guided implant placement was carried out 6\u2009months later. Primary outcome was volume gain. Secondary outcomes included linear ridge changes, surgical and postoperative parameters, implant feasibility and patient\u2010reported outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean volumetric bone gain was 513.1\u2009\u00b1\u2009321.4\u2009mm\n                      <jats:sup>3<\/jats:sup>\n                      , or 112.0%\u2009\u00b1\u200935.0% of the original defect. Mean linear bone gain was 2.2\u2009mm horizontally and 4.7\u2009mm vertically. All implants achieved primary stability with minimal additional augmentation or deviation from the initial digital plan. Surgically, there was one case of transient altered sensation and one case of wound dehiscence. Postoperative pain (worse pain) reached moderate levels that significantly declined to mild levels after Day 4; interference to daily activities significantly reduced by Day 6 and analgesic (NSAIDs) consumption by Day 8.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patient\u2010specific PCL scaffolds demonstrated predictable bone regeneration of moderate size defects with minimal complications, which facilitated precise implant placement, supporting scaffold\u2010guided bone regeneration as a clinically viable and personalised approach in alveolar bone reconstruction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpe.70197","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:06:43Z","timestamp":1788912403000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Alveolar Bone Regeneration Using 3D\u2010Printed, Patient\u2010Specific, Resorbable PCL Scaffold: Prospective Cohort Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4191-4776","authenticated-orcid":false,"given":"Jamil","family":"Alayan","sequence":"first","affiliation":[{"name":"School of Dentistry, Centre for Orofacial Reconstruction and Rehabilitation (COR3) The University of Queensland  Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1504-7517","authenticated-orcid":false,"given":"Reuben","family":"Staples","sequence":"additional","affiliation":[{"name":"School of Dentistry, Centre for Orofacial Reconstruction and Rehabilitation (COR3) The University of Queensland  Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5339-0936","authenticated-orcid":false,"given":"Sa\u0161o","family":"Ivanovski","sequence":"additional","affiliation":[{"name":"School of Dentistry, Centre for Orofacial Reconstruction and Rehabilitation (COR3) The University of Queensland  Herston Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2019.05.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bit.25200"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1088\/1748\u2010605X\/aad916"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13579"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12039"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2013.05.008"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12604"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034517737755"},{"issue":"1","key":"e_1_2_11_10_1","first-page":"7","article-title":"3D\u2010Printed Polycaprolactone Scaffodls Coated With Beta\u2010Tricalcium Phosphate for Bone Regeneration","volume":"123","author":"Chen Z. 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