{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:49:38Z","timestamp":1790506178965,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T00:00:00Z","timestamp":1469491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","award":["ES\/K005723\/1"],"award-info":[{"award-number":["ES\/K005723\/1"]}],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Child Psychology Psychiatry"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Children exposed to maltreatment show neural sensitivity to facial cues signalling threat. However, little is known about how maltreatment influences the processing of social threat cues more broadly, and whether atypical processing of social threat cues relates to psychiatric risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Forty\u2010one 10\u2010 to 14\u2010year\u2010old children underwent a social rejection\u2010themed emotional Stroop task during functional magnetic resonance imaging: 21 children with a documented history of maltreatment (11\u00a0F) and 19 comparison children with no maltreatment history (11\u00a0F). Groups were matched on age, pubertal status, gender,\n                      <jats:styled-content style=\"fixed-case\">IQ<\/jats:styled-content>\n                      , socioeconomic status, ethnicity and reading ability. Classic colour Stroop stimuli were also administered in the same paradigm to investigate potential differences in general cognitive control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with their peers, children who had experienced maltreatment showed reduced activation in the Rejection versus Neutral condition, across circuitry previously implicated in abuse\u2010related posttraumatic stress disorder (\n                      <jats:styled-content style=\"fixed-case\">PTSD<\/jats:styled-content>\n                      ), including the left anterior insula, extending into left ventrolateral prefrontal cortex\/orbitofrontal cortex; left amygdala; left inferior parietal cortex (\n                      <jats:styled-content style=\"fixed-case\">STS<\/jats:styled-content>\n                      ); and bilateral visual association cortex, encompassing the cuneus and lingual gyrus. No group differences in neural or behavioural responses were found for the classic colour Stroop conditions. Significant negative associations between activity in bilateral cuneus and\n                      <jats:styled-content style=\"fixed-case\">STS<\/jats:styled-content>\n                      during the rejection\u2010themed Stroop and higher self\u2010reported\n                      <jats:styled-content style=\"fixed-case\">PTSD<\/jats:styled-content>\n                      symptomatology, including dissociation, were observed in children exposed to maltreatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Our findings indicate a pattern of altered neural response to social rejection cues in maltreated children. Compared to their peers, these children displayed relative hypoactivation to rejection cues in regions previously associated with\n                      <jats:styled-content style=\"fixed-case\">PTSD<\/jats:styled-content>\n                      , potentially reflecting an avoidant coping response. It is suggested that such atypical processing of social threat may index latent vulnerability to future psychopathology in general and\n                      <jats:styled-content style=\"fixed-case\">PTSD<\/jats:styled-content>\n                      in particular.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.12595","type":"journal-article","created":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T02:46:50Z","timestamp":1469501210000},"page":"1165-1173","source":"Crossref","is-referenced-by-count":56,"title":["Altered neural response to rejection\u2010related words in children exposed to maltreatment"],"prefix":"10.1111","volume":"57","author":[{"given":"Vanessa B.","family":"Puetz","sequence":"first","affiliation":[{"name":"Division of Psychology and Language Sciences University College London London UK"},{"name":"Anna Freud Centre London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Essi","family":"Viding","sequence":"additional","affiliation":[{"name":"Division of Psychology and Language Sciences University College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Palmer","sequence":"additional","affiliation":[{"name":"Division of Psychology and Language Sciences University College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip A.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Division of Psychology and Language Sciences University College London London UK"},{"name":"Anna Freud Centre London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachael","family":"Lickley","sequence":"additional","affiliation":[{"name":"Division of Psychology and Language Sciences University College London London UK"},{"name":"Anna Freud Centre London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iakovina","family":"Koutoufa","sequence":"additional","affiliation":[{"name":"Division of Psychology and Language Sciences University College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine L.","family":"Sebastian","sequence":"additional","affiliation":[{"name":"Department of Psychology Royal Holloway University of London Egham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eamon J.","family":"McCrory","sequence":"additional","affiliation":[{"name":"Division of Psychology and Language Sciences University College London London UK"},{"name":"Anna Freud Centre London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2001.1046"},{"key":"e_1_2_7_3_1","volume-title":"DSM\u20105 diagnostic and statistical manual of mental disorders","author":"APA","year":"2013"},{"key":"e_1_2_7_4_1","volume-title":"CTQ Childhood Trauma Questionnaire: A retrospective self\u2010report. 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