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The primary goal of this study was to investigate the impact of the child's primary anxiety diagnosis on changes in clinical severity (of the primary problem) during individual\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      , group\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      and guided parent\u2010led\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      . The secondary goal was to investigate the impact of the child's primary anxiety diagnosis on rates of remission for the three treatment formats.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A sample of 1,253 children (5\u201312\u00a0years; Mage\u00a0=\u00a09.3,\n                      <jats:italic>SD<\/jats:italic>\n                      \u00a0=\u00a01.7) was pooled from\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      trials carried out at 10 sites. Children had a primary diagnosis of generalised anxiety disorder (\n                      <jats:styled-content style=\"fixed-case\">GAD<\/jats:styled-content>\n                      ), social anxiety disorder (So\n                      <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                      ), specific phobia (\n                      <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n                      ) or separation anxiety disorder (\n                      <jats:styled-content style=\"fixed-case\">SAD<\/jats:styled-content>\n                      ). Children and parents completed a semistructured clinical interview to assess the presence and severity of\n                      <jats:styled-content style=\"fixed-case\">DSM<\/jats:styled-content>\n                      \u2010\n                      <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>\n                      psychiatric disorders at preintervention, postintervention and follow\u2010up. Linear mixture modelling was used to evaluate the primary research question and logistic modelling was used to investigate the secondary research question.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In children with primary\n                      <jats:styled-content style=\"fixed-case\">GAD<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">SAD<\/jats:styled-content>\n                      or So\n                      <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                      , there were no significant differences between delivery formats. However, children with primary\n                      <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n                      showed significantly larger reductions in clinical severity following individual\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      compared to group\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      and guided parent\u2010led\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      . The results were mirrored in the analysis of remission responses with the exception that individual\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      was no longer superior to group\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      for children with a primary\n                      <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n                      . The difference between individual and group was not significant when follow\u2010up data were examined separately.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Data show there may be greater clinical benefit by allocating children with a primary\n                      <jats:styled-content style=\"fixed-case\">SP<\/jats:styled-content>\n                      to individual\n                      <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>\n                      , although future research on cost\u2010effectiveness is needed to determine whether the additional clinical benefits justify the additional resources required.\n                    <\/jats:p>\n                  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