{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T09:33:38Z","timestamp":1793180018636,"version":"4.5.0"},"reference-count":48,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,6,20]],"date-time":"2018-06-20T00:00:00Z","timestamp":1529452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["1692\/4\u20101"],"award-info":[{"award-number":["1692\/4\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["4045\/19\u20101"],"award-info":[{"award-number":["4045\/19\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["2698"],"award-info":[{"award-number":["2698"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Child Psychology Psychiatry"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Gilles de la Tourette Syndrome (\n                      <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>\n                      ) is a multifaceted neuropsychiatric developmental disorder with onset in childhood or adolescence and frequent remissions in early adulthood. A rather new emerging concept of this syndrome suggests that it is a disorder of purposeful actions, in which sensory processes and their relation to motor responses (actions) play a particularly important role. Thus, this syndrome might be conceived as a condition of altered \u2018perception\u2010action binding\u2019. In the current study, we test this novel concept in the context of inhibitory control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We examined\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a035 adolescent\n                      <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>\n                      patients and\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a039 healthy controls in a Go\/Nogo\u2010task manipulating the complexity of sensory information triggering identical actions; i.e. to inhibit a motor response. This was combined with event\u2010related potential recordings,\n                      <jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>\n                      data decomposition and source localization.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>\n                      patients showed worse performance compared to controls and larger performance differences when inhibitory control had to be exerted using unimodal visual compared to bimodal auditory\u2010visual stimuli. This suggests increased binding between bimodal stimuli and responses leading to increased costs of switching between responses instructed by bimodal and those instructed by unimodal stimuli. The neurophysiological data showed that this was related to mechanisms mediating between stimulus evaluation and response selection; i.e. perception\u2010action binding processes in the right inferior parietal cortex (\n                      <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content>\n                      40).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Stimulus\u2010action inhibition binding is stronger in\n                      <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>\n                      patients than healthy controls and affects inhibitory control corroborating the concept suggesting that\n                      <jats:styled-content style=\"fixed-case\">GTS<\/jats:styled-content>\n                      might be a condition of altered perception\u2010action integration (binding); i.e. a disorder of purposeful actions.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.12938","type":"journal-article","created":{"date-parts":[[2018,6,20]],"date-time":"2018-06-20T15:34:03Z","timestamp":1529508843000},"page":"953-962","source":"Crossref","is-referenced-by-count":59,"title":["Altered perception\u2010action binding modulates inhibitory control in Gilles de la Tourette syndrome"],"prefix":"10.1111","volume":"60","author":[{"given":"Vanessa","family":"Petruo","sequence":"first","affiliation":[{"name":"Cognitive Neurophysiology Department of Child and Adolescent Psychiatry Faculty of Medicine of the TU Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Bodmer","sequence":"additional","affiliation":[{"name":"Cognitive Neurophysiology Department of Child and Adolescent Psychiatry Faculty of Medicine of the TU Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie C.","family":"Brandt","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics, Center for Brain, Behavior and Metabolism University of L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leoni","family":"Baumung","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics, Center for Brain, Behavior and Metabolism University of L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veit","family":"Roessner","sequence":"additional","affiliation":[{"name":"Cognitive Neurophysiology Department of Child and Adolescent Psychiatry Faculty of Medicine of the TU Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"M\u00fcnchau","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Adult Movement Disorders and Neuropsychiatry Institute of Neurogenetics, Center for Brain, Behavior and Metabolism University of L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Beste","sequence":"additional","affiliation":[{"name":"Cognitive Neurophysiology Department of Child and Adolescent Psychiatry Faculty of Medicine of the TU Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2013.12.003"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27244"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2011.08.024"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2016.07.015"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2009.09.023"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2017.00329"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-08158-9"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1037\/0096-1523.27.4.932"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.20.1.58"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-015-1137-1"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291716001008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.01.054"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/17470210500438304"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv307"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-015-1148-y"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/09297040903150182"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13415-010-0013-y"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.2007.00602.x"},{"key":"e_1_2_7_21_1","first-page":"148","article-title":"Behavioral therapy for Tourette syndrome and chronic tic disorders. 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