{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T04:02:15Z","timestamp":1788926535967,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T00:00:00Z","timestamp":1585353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH091363"],"award-info":[{"award-number":["R01MH091363"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000870","name":"John D. and Catherine T. MacArthur Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000870","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acamh.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child Psychology Psychiatry"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Children reared in institutions experience profound deprivation that is linked to impairments in social communication (SC). However, little is known about the long\u2010term consequences of institutional rearing on SC through adolescence, and how SC deficits relate to broad\u2010spectrum psychopathology. It is also unclear whether early removal from deprivation and placement into socially enriched environments remediates these difficulties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Children reared in Romanian institutions from the Bucharest Early Intervention Project were randomly assigned to care as usual or foster care intervention in early childhood. An age\u2010 and sex\u2010matched group of never\u2010institutionalized children was also recruited. SC data from 208 children at age 8 and 129 children at 16 were collected using the Social Communication Questionnaire. Psychopathology was assessed as saved factor scores for general (P) and specific internalizing (INT) and externalizing (EXT) problems. We examined (a) whether institutional rearing is associated with continued SC deficits into adolescence; (b) whether early placement into foster care mitigates risk for SC problems; and (c) associations between SC and psychopathology from middle childhood (age 8) to adolescence (age 16).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Findings suggest that: (a) institutionally\u2010reared children have significantly more SC problems than never\u2010institutionalized children at age 16; (b) children placed into foster care early in life have fewer problems with reciprocal social interaction compared to those with prolonged institutional rearing; and (c) deficits in SC at age 8 partially account for the link between institutional rearing and general psychopathology at age 16.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Early deprivation is associated with impairments in SC that persist into adolescence, with evidence for the remedial benefit of family\u2010based care in the domain of reciprocal social interaction. Moreover, deficits in SC among ever\u2010institutionalized children in middle childhood may increase the risk of broad\u2010spectrum psychopathology in adolescence, thus providing one putative target for early intervention to safeguard against later psychiatric problems.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.13222","type":"journal-article","created":{"date-parts":[[2020,3,28]],"date-time":"2020-03-28T10:27:27Z","timestamp":1585391247000},"page":"1360-1369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Social communication deficits following early\u2010life deprivation and relation to psychopathology: a randomized clinical trial of foster care"],"prefix":"10.1111","volume":"61","author":[{"given":"Mark","family":"Wade","sequence":"first","affiliation":[{"name":"Department of Applied Psychology and Human Development University of Toronto Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles H.","family":"Zeanah","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Tulane University School of Medicine New Orleans LA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan A.","family":"Fox","sequence":"additional","affiliation":[{"name":"Department of Human Development and Quantitative Methodology University of Maryland College Park MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles A.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Boston Children\u2019s Hospital Harvard Medical School Boston MA USA"},{"name":"Harvard Graduate School of Education Cambridge MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-013-1938-0"},{"key":"e_1_2_7_3_1","volume-title":"Confirmatory factor analysis for applied research","author":"Brown T.A.","year":"2014"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702613497473"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2018.17121383"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/chi.0b013e31812f7d8d"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15328007SEM0803_5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-200205000-00017"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2018.02.009"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2018.11.005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2014.09.040"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-4079"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-005-0005-x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-5834.2010.00550.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2014.11.011"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2017.02.1096"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/imhj.21435"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2018.09.002"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2017.01.007"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10802-014-9855-z"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.40.3.879"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00472"},{"key":"e_1_2_7_23_1","volume-title":"The social communication questionnaire: Manual","author":"Rutter M.","year":"2003"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2007.01792.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04381-8"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/CHI.0b013e318179964f"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30045-4"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-017-1359-z"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0015682"},{"key":"e_1_2_7_30_1","volume-title":"Child maltreatment 2016","author":"U.S. Department of Health and Human Services, C. s. 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