{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T03:28:21Z","timestamp":1792294101990,"version":"4.4.0"},"reference-count":65,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KR1301\u2010A"],"award-info":[{"award-number":["01KR1301\u2010A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KR1301\u2010B"],"award-info":[{"award-number":["01KR1301\u2010B"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acamh.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child Psychology Psychiatry"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The immediate impact of child maltreatment on health and developmental trajectories over time is unknown. Longitudinal studies starting in the direct aftermath of exposure with repeated follow\u2010up are needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We assessed health and developmental outcomes in 6\u2010month intervals over 2\u2009years in 173 children, aged 3\u20135\u2009years at study entry, including 86 children with exposure to emotional and physical abuse or neglect within 6\u2009months and 87 nonmaltreated children. Assessments included clinician\u2010administered, self\u2010 and parent\u2010report measures of psychiatric and behavioral symptoms, development, and physical health. Linear mixed models and latent growth curve analyses were used to contrast trajectories between groups and to investigate the impact of maltreatment features on trajectories.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Maltreated children exhibited greater numbers of psychiatric diagnoses (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u20091.998,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001), externalizing (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u200913.29,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and internalizing (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u200911.70,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) symptoms, impairments in cognitive (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u2009\u221211.586,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001), verbal (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u2009\u221210.687,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001), and motor development (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u2009\u22127.904,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.006), and greater numbers of medical symptoms (\n                      <jats:italic>b<\/jats:italic>\n                      \u2009=\u20091.021,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) compared to nonmaltreated children across all time\u2010points. Lifetime maltreatment severity and\/or age at earliest maltreatment exposure predicted adverse outcomes over time.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The profound, immediate, and stable impact of maltreatment on health and developmental trajectories supports a biological embedding model and provides foundation to scrutinize the precise underlying mechanisms. Such knowledge will enable the development of early risk markers and mechanism\u2010driven interventions that mitigate adverse trajectories in maltreated children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.13550","type":"journal-article","created":{"date-parts":[[2022,3,10]],"date-time":"2022-03-10T02:31:46Z","timestamp":1646879506000},"page":"1027-1045","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Immediate impact of child maltreatment on mental, developmental, and physical health trajectories"],"prefix":"10.1111","volume":"63","author":[{"given":"Sibylle M.","family":"Winter","sequence":"first","affiliation":[{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy  Berlin 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Humboldt\u2010Universit\u00e4t zu Berlin Institute of Medical Psychology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imke","family":"Moebus","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin Institute of Medical Psychology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Murray","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gergana","family":"Karaboycheva","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin Corporate Member of 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