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The reliability and validity of the psychiatric data collected have not yet been examined. This study aims to explore and optimize the reliability\/validity of psychiatric diagnostic constructs in the ABCD study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Parent\u2010and\u2010child\u2010reported psychiatric data for 11,876 children (aged 9.5\u2009\u00b1\u20090.5 at first assessment) were examined over 4\u2009years to derive specific constructs for psychiatric diagnoses using longitudinal information. Rates of psychiatric disorders were calculated and compared to those reported in the epidemiological literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The rates of self\u2010reported psychiatric disorders at any single time point (broad diagnostic construct) were higher than indicated by epidemiological studies. Narrow diagnostic constructs, which required the endorsement of psychiatric disorders at a majority of longitudinal assessments, demonstrated a better rate approximation of literature\u2010reported prevalences for most disorders (e.g. the prevalence of broad obsessive\u2010compulsive disorder (OCD) was 13.3% compared to narrow OCD at 2.6% and a literature\u2010reported prevalence of 2.3%). Analysis of comorbidity, using OCD as a representative example, also showed a better approximation of literature\u2010reported comorbidity rates using the narrow construct, with some exceptions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Self\u2010 or parent\u2010report\u2010based assessments tend to overestimate prevalences of psychiatric disorders in the ABCD Study, particularly when longitudinal data are summed to create lifetime prevalences. Such assessments should be accompanied by more in\u2010depth assessments or clinician\u2010administered structured interviews if using data where accurate disorder classifications are paramount.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.14054","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T04:26:54Z","timestamp":1725856014000},"page":"253-265","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Optimization of self\u2010 or parent\u2010reported psychiatric phenotypes in longitudinal studies"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6776-8626","authenticated-orcid":false,"given":"Franjo","family":"Ivankovic","sequence":"first","affiliation":[{"name":"Analytic and Translational Genetics Unit Massachusetts General Hospital  Boston MA USA"},{"name":"Stanley Center for Psychiatric Research Broad Institute of MIT and Harvard  Cambridge MA USA"},{"name":"Massachusetts General Hospital Center for Genomic Medicine  Boston MA USA"},{"name":"Genetics &amp; Genomics Graduate Program University of Florida Genetics Institute  Gainesville FL USA"},{"name":"Department of Psychiatry, Center for OCD, Anxiety and Related Disorders, McKnight Brain Institute University of Florida College of Medicine  Gainesville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Center for OCD, Anxiety and Related Disorders, McKnight Brain Institute University of Florida College of Medicine  Gainesville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Center for OCD, Anxiety and Related Disorders, McKnight Brain Institute University of Florida College of Medicine  Gainesville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4742-5896","authenticated-orcid":false,"given":"Jeremiah M.","family":"Scharf","sequence":"additional","affiliation":[{"name":"Stanley Center for Psychiatric Research Broad Institute of MIT and Harvard  Cambridge MA USA"},{"name":"Massachusetts General Hospital Center for Genomic Medicine  Boston MA USA"},{"name":"Department of Neurology and Psychiatry Massachusetts General Hospital Psychiatric and Neurodevelopmental Genetics Unit  Boston MA USA"},{"name":"Department of Neurology, Center for Brain Mind Medicine Brigham and Women's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2208-7058","authenticated-orcid":false,"given":"Carol A.","family":"Mathews","sequence":"additional","affiliation":[{"name":"Genetics &amp; Genomics Graduate Program University of Florida Genetics Institute  Gainesville FL USA"},{"name":"Department of Psychiatry, Center for OCD, Anxiety and Related Disorders, McKnight Brain Institute University of Florida College of Medicine  Gainesville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2017.10.010"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40501-017-0108-y"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28593"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852900020381"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/070674370505000904"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pcn5.6"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199612000-00016"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.179.4.324"},{"key":"e_1_2_8_11_1","doi-asserted-by":"crossref","unstructured":"Ivankovic F. 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