{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:40:14Z","timestamp":1791484814870,"version":"4.3.4"},"reference-count":50,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeck Foundation","doi-asserted-by":"publisher","award":["R276\u20102018\u20104581"],"award-info":[{"award-number":["R276\u20102018\u20104581"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH118278"],"award-info":[{"award-number":["R01MH118278"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH119084"],"award-info":[{"award-number":["R01MH119084"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH120170"],"award-info":[{"award-number":["R01MH120170"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH124871"],"award-info":[{"award-number":["R01MH124871"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R56MH129437"],"award-info":[{"award-number":["R56MH129437"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["538\u20102013\u20108864"],"award-info":[{"award-number":["538\u20102013\u20108864"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003748","name":"Svenska S\u00e4llskapet f\u00f6r Medicinsk Forskning","doi-asserted-by":"publisher","award":["PG\u201022\u20100478"],"award-info":[{"award-number":["PG\u201022\u20100478"]}],"id":[{"id":"10.13039\/501100003748","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003186","name":"Fredrik och Ingrid Thurings Stiftelse","doi-asserted-by":"publisher","award":["2021\u201000660"],"award-info":[{"award-number":["2021\u201000660"]}],"id":[{"id":"10.13039\/501100003186","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acamh.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child Psychology Psychiatry"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Avoidant restrictive food intake disorder (ARFID) is a feeding and eating disorder characterized by extremely restricted dietary variety and\/or quantity resulting in serious consequences for physical health and psychosocial functioning. ARFID often co\u2010occurs with neurodevelopmental conditions (NDCs) and psychiatric conditions, but previous data are mostly limited to small clinical samples examining a narrow range of conditions. Here, we examined NDCs and psychiatric conditions in a large, population\u2010based group of children with ARFID.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 30,795 children born 1992\u20132008 in Sweden, ARFID was assessed using parent reports and clinical diagnoses from national health registers. Parents further reported symptoms of NDCs and psychiatric conditions at child age 9 or 12\u2009years. Validated cutoffs were applied to the resulting symptoms scores to identify above\u2010threshold conditions. We then examined whether ARFID was associated with higher symptom scores (19 outcomes) and higher likelihood of above\u2010threshold conditions (15 outcomes) using linear and logistic regressions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most prevalent in children with ARFID were separation anxiety (29.0%), oppositional defiant disorder (19.4%), attention deficit hyperactivity disorder (ADHD, 16.9%), panic disorder (15.3%), and tic disorders (14.8%). For all measured co\u2010occurring conditions, ARFID was associated with significantly higher symptom scores (standardized beta range: 0.6\u20131.5) and higher odds of above\u2010threshold conditions (odds ratio [OR] range: 3.3\u201313.7). The conditions with the highest increase in odds were autism (OR\u2009=\u200913.7) and ADHD (OR\u2009=\u20099.4). We did not find any sex\u2010specific differences in co\u2010occurring conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study highlights the co\u2010occurrence of a broad range of NDCs and psychiatric conditions with ARFID in a large, non\u2010clinical cohort. Our findings underscore that children with ARFID face significant burden from multiple co\u2010existing conditions which should be considered during assessment and treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.14134","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T21:57:56Z","timestamp":1741816676000},"page":"1333-1344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Neurodevelopmental and psychiatric conditions in 600 Swedish children with the avoidant\/restrictive food intake disorder phenotype"],"prefix":"10.1111","volume":"66","author":[{"given":"Manda","family":"Nyholmer","sequence":"first","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Louis","family":"Wronski","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"},{"name":"Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School  Boston MA USA"},{"name":"Translational Developmental Neuroscience Section, Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine TU Dresden  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liv","family":"Hog","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3765-2067","authenticated-orcid":false,"given":"Ralf","family":"Kuja\u2010Halkola","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Lichtenstein","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Lundstr\u00f6m","sequence":"additional","affiliation":[{"name":"Gillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, Sahlgrenska Academy University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Larsson","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"},{"name":"School of Medical Sciences \u00d6rebro University  \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5161-4182","authenticated-orcid":false,"given":"Mark J.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia M.","family":"Bulik","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Psychiatry University of North Carolina at Chapel Hill  Chapel Hill NC USA"},{"name":"Department of Nutrition University of North Carolina at Chapel Hill  Chapel Hill NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9901-4984","authenticated-orcid":false,"given":"Lisa","family":"Dinkler","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1375\/twin.14.6.495"},{"key":"e_1_2_10_4_1","first-page":"237","article-title":"Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents","volume":"5","author":"Angold A.","year":"1995","journal-title":"International Journal of Methods in Psychiatric Research"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcv2.12160"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23261"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199910000-00011"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2815"},{"key":"e_1_2_10_10_1","unstructured":"Castro O.A.C.(2023).\u201cIt's about survival love and care\u201d \u2013 When ARFID takes over life. [\u201cDet handlar om \u00f6verlevnad k\u00e4rlek och omsorg\u201d \u2013 N\u00e4r ARFID tar \u00f6ver livet]. Institutionen f\u00f6r psykologi Lunds Universitet."},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40337-023-00939-0"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2022.4612"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.appet.2021.105735"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcv2.12094"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2013.11.013"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqy342"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-023-00441-6"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10578-017-0746-8"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0230623"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-014-2095-9"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23191"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-022-01404-6"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2021.3861"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/21677026221144255"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-014-0622-z"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-13-233"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2006.11.006"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23027"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/0706743716640757"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-017-1563-0"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40337-014-0021-3"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-017-0972-4"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.680298"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2017.10.008"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.13410"},{"key":"e_1_2_10_36_1","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2022"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaacop.2023.05.001"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.2964"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102440"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.671631"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.appet.2020.104643"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-021-01161-7"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0028931"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2020.0680"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23004"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCO.0000000000000641"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.22939"},{"key":"e_1_2_10_48_1","volume-title":"International Classification\u00a0of Diseases Eleventh Revision (ICD\u201011)","author":"World Health Organization","year":"2022"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2024.6065"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23016"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/15374416.2020.1738236"}],"container-title":["Journal of Child Psychology and Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acamh.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jcpp.14134","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T19:07:35Z","timestamp":1762196855000},"score":1,"resource":{"primary":{"URL":"https:\/\/acamh.onlinelibrary.wiley.com\/doi\/10.1111\/jcpp.14134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,12]]},"references-count":50,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/jcpp.14134"],"URL":"https:\/\/doi.org\/10.1111\/jcpp.14134","archive":["Portico"],"relation":{},"ISSN":["0021-9630","1469-7610"],"issn-type":[{"value":"0021-9630","type":"print"},{"value":"1469-7610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,12]]},"assertion":[{"value":"2024-12-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}