{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:33:59Z","timestamp":1782938039243,"version":"3.54.5"},"reference-count":72,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T00:00:00Z","timestamp":1757289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T00:00:00Z","timestamp":1757289600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acamh.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Child Psychology Psychiatry"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Comorbidity and heterogeneity in psychiatric disorders may stem from a general psychopathology (p) factor influenced by both genetic and environmental factors. Although the relative contributions of these influences on psychopathology are established, the longitudinal associations between the p\u2010factor and specific environmental exposures and the aetiology of these associations across development are not well understood. Here, we examine whether twin\u2010rated home environment contributes to changes in the p\u2010factor over time or, conversely, whether the p\u2010factor influences twin\u2010rated home environment, reflecting potential evocative gene\u2013environment processes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data were obtained from the Twins Early Development Study (TEDS). Cross\u2010lagged panel analyses were conducted separately to ascertain the direction of associations between parent\u2010rated p, twin\u2010rated p, and twin\u2010rated home environment (chaos at home and parental discipline) at ages 9, 12, and 16 (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u20096,213). Biometric autoregressive cross\u2010lagged twin models were used to assess the aetiology of these associations, and MZ differences analyses were used to control for familial effects.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both parent\u2010rated and twin\u2010rated p\u2010factor and twin\u2010rated home environment were stable over time, although the twin\u2010rated p\u2010factor (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009.44 [0.42, 0.46]\u2013.40 [0.37, 0.41]) was more variable than the parent\u2010rated p\u2010factor (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009.72 [0.71, 0.74]\u2013.63 [0.61, 0.64]). Twin\u2010rated home environment was more variable than p\u2010factor in all cross\u2010lagged models (phenotypic and MZ differences). Small, significant bidirectional associations were found between the p\u2010factor and twin\u2010rated home environment, with stronger cross\u2010lagged paths from the p\u2010factor to the twin\u2010rated home environment than vice versa. These longitudinal associations persisted over time, though attenuated for parent\u2010rated p\u2010factor. Genetic analyses revealed that bidirectional cross\u2010lagged paths were largely explained by shared environmental factors, with a smaller proportion explained by genetic factors. This pattern of results was confirmed in MZ difference analyses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings suggest a dynamic and bidirectional relationship between p\u2010factor and twin\u2010rated home environment across development, predominantly influenced by shared environmental factors. Changes in one can affect the other, highlighting the complexity of psychopathology's environmental influences. This underscores the need for further investigation into gene\u2013environment interplay to inform prevention and intervention strategies for psychopathology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jcpp.70046","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T10:26:57Z","timestamp":1757327217000},"page":"266-281","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["How are children's perceptions of the home environment associated with a general psychopathology factor across childhood?"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5796-8229","authenticated-orcid":false,"given":"Jack K.","family":"Nejand","sequence":"first","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Malanchini","sequence":"additional","affiliation":[{"name":"School of Biological and Behavioural Sciences Queen Mary, University of London  London UK"},{"name":"Social, Genetic and Developmental Psychiatry Centre Institute of Psychiatry, Psychology and Neuroscience, King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9863-177X","authenticated-orcid":false,"given":"Ivan","family":"Voronin","sequence":"additional","affiliation":[{"name":"\u00c9cole de Psychologie Universit\u00e9 Laval  Quebec City QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6458-0700","authenticated-orcid":false,"given":"Thalia C.","family":"Eley","sequence":"additional","affiliation":[{"name":"Social, Genetic and Developmental Psychiatry Centre Institute of Psychiatry, Psychology and Neuroscience, King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5139-065X","authenticated-orcid":false,"given":"Kaili","family":"Rimfeld","sequence":"additional","affiliation":[{"name":"Social, Genetic and Developmental Psychiatry Centre Institute of Psychiatry, Psychology and Neuroscience, King's College London  London UK"},{"name":"Department of Psychology, Royal Holloway University of London  Surrey UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.13659"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.13113"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcv2.12100"},{"key":"e_1_2_10_5_1","volume-title":"The development of a questionnaire for use in epidemiological studies of depression in children and adolescents","author":"Angold A.","year":"1987"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1088868313498308"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005653411471"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31013-X"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.childyouth.2016.09.006"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11336-010-9200-6"},{"key":"e_1_2_10_11_1","volume-title":"Home observation for measurement of the environment: Administration manual","author":"Caldwell B.M.","year":"2003"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702613497473"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2018.17121383"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10802-014-9872-y"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.112.4.558"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecresq.2015.03.001"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.2307\/1127215"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10862-012-9288-3"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2011.0011"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579498001709"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00179"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2010.02227.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.3.574"},{"key":"e_1_2_10_24_1","doi-asserted-by":"crossref","unstructured":"Frick P.J.(2004).The inventory of callous\u2010unemotional traits. 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